astex pharmaceuticals (ASTX:NASDAQ GS)

Executive Profile*

Background*

Dr. James S. J. Manuso, Jim, PhD, MBA has been Chairman and Chief Executive Officer of Astex Pharmaceuticals, Inc (formerly SuperGen Inc) since January 1, 2004. Dr. Manuso serves as the Chief Business Officer of Symbiontics, Inc. and ZyStor Therapeutics, Inc. He served as the President of Astex Pharmaceuticals, Inc. from January 1, 2004 to July 2011. He served as the Chief Executive Officer of Astex Pharmaceuticals, Inc. from September 2003 to December 2003. He served ... as Consultant of Astex Pharmaceuticals, Inc. since September 5, 2003. Dr. Manuso Co-founded Regalen Inc. (formerly known as Galenica Pharmaceuticals, Inc) and served as its President and Chief Executive Officer until September 5, 2003. He co-founded Manuso, Alexander & Associates, Inc. and served as its President since 1992. He co-founded PrimeTech Partners in 1998 and served as its General Partner from 1998 to 2002. He co-founded ZyStor Therapeutics, Inc. Dr. Manuso was a Managing General Partner of The Channel Group LLC, an international life sciences corporate advisory firm. From 1984 to 1992, he developed and consulted to biotechnology companies and managed family investments. From 1974 to 1983, Dr. Manuso served as an Officer of The Equitable Companies, serving in the capacities of Acting Medical Director and Director of Health Care Planning and Development. He served as the Vice President of the Greater San Francisco Bay Area Leukemia & Lymphoma Society. Dr. Manuso serves as the Vice Chairman of Symbiontics, Inc. and ZyStor Therapeutics, Inc. He served as Vice Chairman of Quark Biotech, Inc. He serves as a Director of KineMed, Inc. Dr. Manuso has been a Director at Astex Pharmaceuticals, Inc. since February 2001 and Novelos Therapeutics, Inc. since August 2007. He serves as a Director of Regalen Inc. and Biotechnology Industry Organization. He He served as a Director of Merrion Pharmaceuticals Limited from July 2006 to September 2008. He served as a Director of Galenica Pharmaceuticals, Symbiontics, Inc., and the greater San Francisco Bay Area Chapter of the Leukemia and Lymphoma Society. Dr. Manuso also served on the boards of Inflazyme Pharmaceuticals, Inc., and Supratek Pharma, Inc. He is the author of over 30 chapters, articles and books on topics including health care cost containment and biotechnology company management. He taught and lectured at Columbia, NYU, Georgetown University, Polytechnic University and Waseda University (Japan). Dr. Manuso holds an A.B. in Economics and Chemistry from New York University, a Ph.D in Experimental Psychophysiology from the Graduate Faculty of The New School University, a Certificate in Health Systems Management from Harvard Business School, and an Executive MBA from Columbia Business School.

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