Executive Profile

L. Patrick Gage Ph.D. Director of Permeon Biologics, Permeon Biologics, Inc.

Age	Total Calculated Compensation	This person is connected to 14 Board Members in 14 different organizations across 18 different industries. See Board Relationships
70	--

Background

Dr. L. Patrick Gage, Ph.D., Pat, was a Venture Partner of Flagship Ventures. Dr. Gage focused on identifying drug discovery and drug development ventures and helping management teams build these ventures into successful biopharmaceutical leaders. He has been a leader and a veteran in the pharmaceutical and biotech sectors since 1971. He founded enGage Biotech Consulting in July 2002. He served as Interim Chief Executive Officer of PDL BioPharma, Inc. from October 1, ... 2007 to May 28, 2008. Dr. Gage joined Genetics Institute, LLC in November 1989 as the Senior Vice President of Scientific Affairs and also served as its Executive Vice President since January 1990 and Chief Operating Officer since November 1993. He also served as the Head of Research and Development at Genetics Institute, LLC from 1989 to 1998 and served as its President since 1997. Dr. Gage served as the Senior Vice President of Science and Technology at Wyeth since 2000. He served as the President of Wyeth Research from 1998 to 2002. He served as the Senior Vice President of Science and Technology at Wyeth Research. Dr. Gage served as the Chief Scientific Officer at Wyeth Corporate and as an Advisor to its Chairman and Chief Executive Officer. He served at Wyeth until June 2002. Dr. Gage also spent 18 years at Hoffmann-La Roche, Inc. from 1971 and 1989 in various scientific and management positions including Vice President of Exploratory Research from 1985 to 1989. Dr. Gage has nearly 40 years of experience in the life science industry. Dr. Gage serves as the Executive Chairman of Virdante Pharmaceuticals, Inc. He serves as the Chairman of Compound Therapeutics, Cyotkinetics and Dublin (IE) Molecular Medicine Centre. He has been the Chairman at Tetraphase Pharmaceuticals, Inc. since January 5, 2012, Cytokinetics, Incorporated since March 16, 2010, Neose Technologies Inc. since May 2006 and Adnexus Therapeutics Inc. since September 26, 2006. He serves as the Chairman of Science Advisory Board at Center for Advanced Biotechnology and Medicine. He served as the Chairman of the Board of Protein Design Labs Inc. from April 9, 2007 to October 1, 2007 and served as its Director from March 2003 to May 28, 2008. He served as the Chairman of Acceleron Pharma, Inc. and Wyeth Corporate. Dr. Gage has been a Director of Neose Technologies Inc. since October 2002 and Cytokinetics, Incorporated since November 2009. He serves as a Director of Adnexus Therapeutics Inc., Tetraphase Pharmaceuticals, Inc., Biotechnology Institute, The and Alvine Pharmaceuticals, Inc. He serves as a Member of Scientific Advisory Board at Functional Genetics, Inc. He served as a Director of ArQule Inc. He has been a Member of Therapeutic Advisory Board at aTyr Pharma Inc. since March 1, 2011. Dr. Gage serves on the Board of several non-profits, including a Director of The Biotechnology Institute and The Philadelphia Orchestra Association. He serves as a Member of the Life Sciences Advisory Board at Warburg Pincus LLC. He serves on the advisory board of Pappas Ventures. Dr. Gage is also an Advisor and serves on the Board of the Life Sciences Research Foundation. He is also the Scientific Advisor and a Founding Member of the Advisory Board of PerkinElmer Life Sciences, and the Scientific Advisor at Analytical Sciences. He serves as a Director of Permeon Biologics Inc. He served as a Director of Wyeth Corporate. He served as a Director of Immune Control Inc. Dr. Gage served as a Director of Merck Serono S.A (Serono S.A) since May 2004. Dr. Gage holds a B.S. degree in Physics in 1964 from the Massachusetts Institute of Technology and a Ph.D. degree in Biophysics from the University of Chicago in 1969. He completed his postdoctoral research at the Carnegie Institution of Washington, Baltimore, in 1971.

Corporate Headquarters 101 Main Street Cambridge, Massachusetts 02142 United States Phone: 617-300-8500 Fax: 617-300-8501 Board Members Memberships Chairman Adnexus Therapeutics Inc. Former Director Immune Control Inc. Director The Philadelphia Orchestra Association Former Director Acceleron Pharma, Inc. Director Biotechnology Institute, The Director Alvine Pharmaceuticals, Inc. Director Corridor Pharmaceuticals, Inc. Executive Chairman Virdante Pharmaceuticals, Inc. 1996-1999 Former Director ArQule Inc. 2002-Present Non-Executive Chairman, Chairman of Scientific Review Committee, Member of Corporate Governance Committee and Member of Compensation Committee Neose Technologies Inc. 2003-2008 Former Chairman, Interim Chief Executive Officer, Independent Director, Member of Equity Grant Committee, Member of Compliance Committee and Member of Scientific Review Committee PDL BioPharma, Inc. 2004-N/A Former Director and Member of Compensation Committee Merck Serono S.A. 2009-Present Chairman of The Board, Member of Compensation & Talent Committee and Member of Nominating & Governance Committee Cytokinetics, Incorporated 2011-Present Chairman of the Board and Chairman of Nominating & Corporate Governance Committee Tetraphase Pharmaceuticals, Inc. Education BS 1964 Massachusetts Institute of Technology PhD 1969 The University of Chicago Other Affiliations Warburg Pincus LLC Flagship Ventures ArQule Inc. Cytokinetics, Incorporated Genetics Institute, LLC Neose Technologies Inc. Wyeth, LLC PDL BioPharma, Inc. The University of Chicago Merck Serono S.A. Hoffmann-La Roche Inc. Functional Genetics, Inc. Massachusetts Institute of Technology Adnexus Therapeutics Inc. Immune Control Inc. The Philadelphia Orchestra Association Center for Advanced Biotechnology and Medicine Acceleron Pharma, Inc. Dublin Molecular Medicine Center Biotechnology Institute, The Tetraphase Pharmaceuticals, Inc. Alvine Pharmaceuticals, Inc. aTyr Pharma Inc. Corridor Pharmaceuticals, Inc. Virdante Pharmaceuticals, Inc.

Annual Compensation There is no Annual Compensation data available. Stocks Options There is no Stock Options data available. Total Compensation There is no Total Compensation data available.

COMPETITOR COMPENSATION

There is no Competitor Compensation data available.