Executive Profile

Jonathan Todd Silverstein J.D. General Partner, Co-Head of Global Private Equity Business, and Chairman, OrbiMed Advisors, L.L.C.

Age	Total Calculated Compensation	This person is connected to 13 Board Members in 13 different organizations across 22 different industries. See Board Relationships
45	--

Background

Mr. Jonathan Todd Silverstein J.D. is the General Partner, Co-Head of Global Private Equity Business, and Chairman of OrbiMed Advisors, L.L.C. Mr. Silverstein serves as Chairman, Partner and General Partner of OrbiMed Israel Partners. He serves as General Partner of Caduceus Private Investments III, L.P.; Caduceus Private Investments, L.P. and of Caduceus Private Investments II, L.P. Mr. Silverstein has been the General Partner of OrbiMed Advisors L.L.C. since 1998. ... From 1996 to 1999, he served as the Director of Life Sciences in the investment banking department at Sumitomo Bank Limited, where he was In Charge of strategic alliances, mergers and acquisitions in the biotechnology sector. From 1994 to 1996, Mr. Silverstein served as an Associate at Hambro Resource Development. Mr. Silverstein serves as the Chairman of the Board of Gelesis, Inc. He serves as the Chairman of Cerapedics, Inc. He serves as Chairman of Alexion Montréal Corp. (formerly Enobia Pharma, Inc) and has been its Director since September 12, 2007. He has been Director of DFine, Inc. since July 2010. He has been a Director of Adiana, Inc. since August 2005. He serves as Director at Relypsa, Inc. He serves as Director of Glaukos Corporation, superDimension Inc., Roka Bioscience, Inc., and superDimension, Ltd. He has been a Director of Intercept Pharmaceuticals, Inc. since August 9, 2012. He serves as a Member of Advisory Board of Hadasit Medical Research Services and Development Ltd. He served as Director of Nxstage Medical, Inc., from July 2008 to January 24, 2011. He served as a Director of Insulet Corporation since February 2006. Mr. Silverstein served as Independent outside Director of Avanir Pharmaceuticals, Inc. from September 2004 to August 10, 2007. He served as a Director of Auxilium Pharmaceuticals Inc., from November 2003 to June 2004. He served as Director of Given Imaging Ltd. from September 2000 to May 2006. He served as Director of Predix Pharmaceuticals Holdings Inc. since August 2003. He served as a member of the board of directors of Predix Pharmaceuticals Ltd. from November 2000 to August 2003 and Predix Pharmaceuticals, Inc. from September 2001 to August 2003. He served as a Director of DOV Pharmaceutical Inc. from December 22, 2003 to May 22, 2006. He served as Director of Emphasys Medical Inc. since June 2004. He served as a Director of LifeCell Corporation from April 2002 to December 22, 2003 and Orthovita Inc. from September 2002 to November 3, 2003. He served as Director of Cerexa, Inc., Peninsula Pharmaceuticals Inc. and Bioenvision, Inc. He served as a Director/Observer in an additional dozen companies including: Auxillium. Mr. Silverstein has a Bachelor of Arts degree in Economics from Denison University, Juris Doctor Degree from University of San Diego School of Law and MBA from the University of San Diego.

Corporate Headquarters 601 Lexington Avenue at 53rd Street New York, New York 10022-4629 United States Phone: 212-739-6400 Fax: 212-739-6444 Board Members Memberships Director superDimension, Ltd. General Partner, Co-Head of Global Private Equity Business, and Chairman OrbiMed Advisors, L.L.C. Former Director Predix Pharmaceuticals, Inc., prior to acquisition by Physiome Sciences, Inc. Director Bioenvision, Inc. Former Director Auxilium Pharmaceuticals Inc. Director Peninsula Pharmaceuticals Inc. Director Glaukos Corporation Chairman CeraPedics, Inc. Former Director Cerexa, Inc. Director Gelesis, Inc. Director Roka Bioscience, Inc. Director superDimension, Inc. Chairman, Partner, and General Partner OrbiMed Israel Partners 2000-2006 Former Director Given Imaging Ltd. 2002-2003 Former Director LifeCell Corporation 2002-2003 Former Director Orthovita Inc. 2003-N/A Former Director and Chairman of Compensation Committee Predix Pharmaceuticals Holdings, Inc. 2003-2006 Former Director DOV Pharmaceutical Inc. 2004-2007 Former Independent Outside Director Avanir Pharmaceuticals, Inc. 2004-N/A Former Director Emphasys Medical, Inc. 2005-N/A Former Director Adiana, Inc. 2006-N/A Former Director and Member of Compensation Committee Insulet Corporation 2007-Present Chairman Alexion Montréal Corp. 2008-2011 Former Director and Chairman of Nominating & Corporate Governance Committee Nxstage Medical, Inc. 2010-Present Director DFINE Inc. 2010-Present Director Relypsa, Inc. 2012-Present Director, Member of Nominating & Governance Committee and Member of Audit Committee Intercept Pharmaceuticals, Inc. Education BA Denison University MBA University Of San Diego JD University of San Diego School of Law Other Affiliations Adiana, Inc. LifeCell Corporation Orthovita Inc. Predix Pharmaceuticals Holdings, Inc. superDimension, Ltd. Alexion Montréal Corp. Nxstage Medical, Inc. Avanir Pharmaceuticals, Inc. Given Imaging Ltd. Insulet Corporation Predix Pharmaceuticals, Inc., prior to acquisition by Physiome Sciences, Inc. Bioenvision, Inc. DOV Pharmaceutical Inc. Auxilium Pharmaceuticals Inc. Hadasit Medical Research Services and Development Ltd. Peninsula Pharmaceuticals Inc. Emphasys Medical, Inc. Glaukos Corporation Caduceus Private Investments, L.P. Denison University University Of San Diego Caduceus Private Investments II, L.P. Intercept Pharmaceuticals, Inc. CeraPedics, Inc. University of San Diego School of Law Cerexa, Inc. DFINE Inc. Caduceus Private Investments III, L.P. Gelesis, Inc. Relypsa, Inc. Roka Bioscience, Inc. superDimension, Inc. OrbiMed Israel Partners

Annual Compensation There is no Annual Compensation data available. Stocks Options There is no Stock Options data available. Total Compensation There is no Total Compensation data available.

COMPETITOR COMPENSATION

There is no Competitor Compensation data available.