Executive Profile

Ernest Mario Ph.D. Chairman and Chief Executive Officer, CAPNIA, Inc.

Age	Total Calculated Compensation	This person is connected to 28 Board Members in 28 different organizations across 30 different industries. See Board Relationships
74	--

Background

Dr. Ernest Mario Ph.D., Ernie, has been Chief Executive Officer of Capnia Inc since August 2007. Dr. Mario serves as an Advisor of TAXIS Pharmaceuticals, Inc. He is a Venture Partner at Pappas Ventures. He is an Adjunct Professor of Pharmacy at the University of Rhode Island. He serves at GlaxoSmithKline plc, and GlaxoSmithKline LLC. He has 40 years of experience in the pharmaceutical industry. He served as Chief Executive Officer of Reliant Pharmaceuticals Inc. from ... April 2003 to August 2007. He served as the Chief Executive Officer at Intrabiotics Pharmaceuticals Inc. from April 2002 to June 2005. Dr. Mario served as the Chief Executive Officer at Apothogen Inc. from January 2002 to April 2002. Prior to joining Apothogen in 2002, he served as the Chief Executive Officer at Alza Corporation from November 1997 to December 2001 and Chief Executive Officer from August 1993 to November 1997. He served as the Chief Executive Officer at Glaxo Holdings PLC from May 1989 to March 1993. Dr. Mario served as Chief Executive Officer at Glaxo Inc. from 1988 to 1989 and as the President and Chief Operating Officer at Glaxo Inc. from 1986 to 1988. Prior to 1989, he held management positions overseeing operations in quality control, manufacturing, and devices at Smith Kline and Squibb. Dr. Mario served as the President and Chief Executive Officer at Squibb Corp. from 1977 to 1985. He served as the Chief Executive Officer of Alza & Glaxo Pharmaceuticals. He began his career in 1966 as a Pharmaceutical Researcher at Strasenburgh Laboratories in Rochester, New York. During the course of his career, He has served as the Chief Executive Officer of several pharmaceutical companies. Dr. Mario has been Chairman of Capnia Inc. since August 2007. He serves as the Chairman of at Peninsula Skincare Labs, Inc. He served as the Chairman of Pharmaceutical Product Development Inc. at AbCRO, Inc. from 2003 to July 2007. During the course of his career, He has served as the Chairman of several pharmaceutical companies. He served as Chairman of Reliant Pharmaceuticals Inc. from April 2003 to August 2007. He served as the Chairman at Intrabiotics Pharmaceuticals Inc. from April 2002 to June 2005. Dr. Mario served as the Chairman at Apothogen Inc. from January 2002 to April 2002. Prior to joining Apothogen in 2002, he served as the Chairman at Alza Corporation from November 1997 to December 2001 and Co-Chairman from August 1993 to November 1997. He served as the Deputy Chairman at Glaxo Holdings PLC from January 1992 to March 1993. Prior to that, Dr. Mario served as the Chairman at Glaxo Inc. from 1988 to 1989 and as the President and Chief Operating Officer at Glaxo Inc. from 1986 to 1988. He served as Chairman of Duke University Health System. He serves as a Member of Scientific Advisory Board at Epiphany Biosciences, Inc. He has been a Director of VIVUS Inc. since April 2012. Dr. Mario serves as a Director of TAXIS Pharmaceuticals, Inc. He serves as Member of Advisory Board of Metalmark Capital LLC where he focuses on healthcare investments. He serves as a Director of Avid Celgene. Dr. Mario is a Member of the Executive Advisory Board of Linden LLC. He has been a Director of Pharmaceutical Product Development Inc. since 1993, He also previously served as the chairman of multinational CRO Pharmaceutical Product Development (PPD) from 1993 to 2011, a Director of Philips Ultrasound, Inc. (also known as Advanced Technology Labs Inc) since December 4, 1996 and Squibb since 1984. Dr. Mario has been a Director of Maxygen Inc. since July 2001. He has been the Chairman of the Board at Chimerix, Inc. February 2013. He has been Lead Director of Pharmaceutical Product Development Inc. since July 2009. He has been Director of Delpor, Inc since January 19, 2012. He has been a Director of Boston Scientific Corp. since October 2001, Celgene Corporation since August 22, 2007 and Avid Radiopharmaceuticals, Inc. since June 6, 2007. He has been a Director of Tonix Pharmaceuticals Holding Corporation since October 2011. He also serves on the Board of several publicly traded corporations. He serves as a Director of Alexza Molecular Delivery Corporation, Prestwick Pharmaceuticals, Inc. and Silver Bullet Therapeutics, Inc. He served as a Director of Taris Biomedical, Inc. He serves as an Advisor to The Ernest Mario School of Pharmacy at Rutgers University. He serves as Member of Board of Overseers of Rutgers University Foundation. He serves as Trustee of Duke University. He has been a Director of Alza Corp., since 1993. He is a Trustee of Rockefeller University. He serves as Gladstone Foundation. Dr. Mario is active in numerous educational and healthcare organizations, including Duke University, where he serves as a Director of the Duke University Health System Board and Chairman at the American Foundation for Pharmaceutical Education. He has been a Director of Xenoport, Inc. since June 18, 2012 and also Director of Balance Therapeutics. He served as Director of Millennium Pharmaceuticals, Inc. He served as Director of Avocet Medical Inc. Dr. Mario served as a Director of Intrabiotics Pharmaceuticals Inc. until June 2005 and Reliant Pharmaceuticals, Inc. until June 30, 2007. He served as a Director of Oculex Pharmaceuticals, Inc. since March 2000. He served as Director of Alexza Pharmaceuticals Inc. from September 2001 to July 18, 2007. Dr. Mario served as a Director of COR Therapeutics Inc. since September 1995. He served as a Director of SonoSite Inc. from December 1999 to May 15, 2003 and Catalytica Inc. since 1996. He was a Member of Pappas Ventures' Scientific Advisory Board for 9 years starting in 2002 and a Member of Scientific Advisory Board of Pappas Ventures since 2002. Dr. Mario served as a Director of Orchid Cellmark Inc. (also known as Orchid Biosciences) since March 2000. He served as a Director of Cepheid (also known as Cepheid Inc.) and Catalytica Energy Systems Inc. In 2007. Dr. Mario was awarded the Remington Medal of Honor, the pharmacy profession’s highest honor. He also holds Honorary Doctorates from the University of Rhode Island and Rutgers University. Dr. Mario also holds a Ph.D. degree in Physical Sciences from the University of Rhode Island. He also holds an M.S. from the University of Rhode Island and a B.S. degree in Pharmacy from Rutgers University.

Corporate Headquarters 2445 Faber Place Palo Alto, California 94303 United States Phone: 650-213-8444 Fax: 650-213-8383 Board Members Memberships Director Avocet Medical Inc. Former Chairman of the Board and Chairman of Nominating and Corporate Governance Committee Intrabiotics Pharmaceuticals Inc. Former Director Millennium Pharmaceuticals, Inc. Director Catalytica Energy Systems Inc. Former Chairman Reliant Pharmaceuticals, Inc. Chairman and Chief Executive Officer CAPNIA, Inc. Trustee Duke University Director Prestwick Pharmaceuticals, Inc. Member of Board of Overseers Rutgers University Foundation Former Director TARIS BioMedical, Inc. Advisor adn Director TAXIS Pharmaceuticals, Inc. Director Silver Bullet Therapeutics, Inc. Chairman of The Board of Directors Peninsula Skincare Labs, Inc. 1993-Present Lead Independent Director, Chairman of Nominating & Governance Committee and Member of Compensation Committee Pharmaceutical Product Development, LLC 1993-N/A Chairman ALZA Corporation 1995-N/A Former Director COR Therapeutics, Inc. 1996-N/A Former Director Catalytica, Inc. 1996-Present Director Philips Ultrasound, Inc. 1999-2003 Former Director SonoSite Inc. 2000-Present Director Oculex Pharmaceuticals, Inc. 2000-N/A Former Director Orchid Cellmark Inc. 2001-Present Director, Chairman of Compensation Committee, Member of Audit Committee and Member of Corporate Governance & Nominating Committee Maxygen, Inc. 2001-Present Independent Director, Chairman of Executive Compensation & Human Resources Committee and Member of Audit Committee Boston Scientific Corporation 2001-2007 Former Director and Member of Compensation Committee Alexza Pharmaceuticals Inc. 2007-Present Director, Member of Executive Committee and Member of Nominating & Governance Committee Celgene Corporation 2007-Present Director Avid Radiopharmaceuticals, Inc. 2011-Present Director and Member of Compensation Committee Tonix Pharmaceuticals Holding Corp 2012-Present Director VIVUS Inc. 2012-Present Director and Member of Nominating & Corporate Governance Committee Xenoport, Inc. 2012-Present Director Delpor, Inc. 2012-Present Director Kindred Biosciences, Inc. 2013-Present Chairman and Member of Nominating & Corporate Governance Committee Chimerix, Inc. Education Honorary Doctorate Rutgers, The State University of New Jersey BS Rutgers, The State University of New Jersey Honorary Doctorate University Of Rhode Island MS University Of Rhode Island PhD University Of Rhode Island Unknown/Other Education Rutgers College of Pharmacy Other Affiliations Pappas Ventures Metalmark Capital LLC Avocet Medical Inc. Catalytica, Inc. Cepheid COR Therapeutics, Inc. Intrabiotics Pharmaceuticals Inc. Millennium Pharmaceuticals, Inc. VIVUS Inc. Philips Ultrasound, Inc. Pharmaceutical Product Development, LLC Maxygen, Inc. Xenoport, Inc. Oculex Pharmaceuticals, Inc. Orchid Cellmark Inc. ALZA Corporation Celgene Corporation GlaxoSmithKline plc Boston Scientific Corporation SonoSite Inc. Catalytica Energy Systems Inc. Squibb Corp. Reliant Pharmaceuticals, Inc. Apothogen, Inc. Linden LLC Chimerix, Inc. Burrill Biotechnology Capital Fund I, L.P. Burrill Biotechnology Capital Fund II, L.P. Duke University Rutgers, The State University of New Jersey University Of Rhode Island Prestwick Pharmaceuticals, Inc. Rutgers University Foundation Rutgers College of Pharmacy AbCRO, Inc. Avid Radiopharmaceuticals, Inc. GlaxoSmithKline LLC Alexza Pharmaceuticals Inc. Burrill Life Sciences Capital Fund II, L.P. Epiphany Biosciences, Inc. TARIS BioMedical, Inc. TAXIS Pharmaceuticals, Inc. Silver Bullet Therapeutics, Inc. Delpor, Inc. Tonix Pharmaceuticals Holding Corp Peninsula Skincare Labs, Inc. Kindred Biosciences, Inc.

Annual Compensation There is no Annual Compensation data available. Stocks Options There is no Stock Options data available. Total Compensation There is no Total Compensation data available.

COMPETITOR COMPENSATION

There is no Competitor Compensation data available.