Executive Profile

Jean M. George General Partner, Lightstone Ventures

Age	Total Calculated Compensation	This person is connected to 8 Board Members in 8 different organizations across 10 different industries. See Board Relationships
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Background

Ms. Jean M. George is General Partner of Advanced Technology Ventures. Ms. George joined Advanced Technology Ventures in 2002 and serves as its East Coast Lead Partner for Healthcare Investments. She is a General Partner of Lightstone Ventures. She focuses on biopharmaceutical and medical device investments. Ms. George accesses new deals in the life sciences and therapeutic device markets, identifying innovations viable for commercialization. She has more than 20 years ... of biopharmaceutical industry experience, including 10 years at Genzyme Corporation. At Genzyme, she held a variety of operational roles in marketing, product development, and business development, including Vice President of Global Sales and Marketing. She was the Founder and Vice President of Genzyme's Tissue Repair Division and was responsible for identifying new product opportunities and potential acquisition candidates. In 1998, Ms. George joined the venture capital community and lead BancBoston Ventures’ life sciences investments. She has an extensive operating and investment background, she also spent six years working in chemistry and bioresearch. Ms. George worked at BancBoston Capital, Inc. She served as Chairman of Zeltiq Aesthetics, Inc. and has been its Director since 2005. She serves as a Director of Calithera Biosciences Inc., Onyx Therapeutics, Inc., Thrasos Innovation Inc., Acceleron Pharma Inc. Five Prime Therapeutics, Hydra Biosciences Inc. and Juniper Medical. Ms. George has been an Independent Director of Portola Pharmaceuticals, Inc. since October 2005. She represents on the boards of Catabasis and Verastem. She served as a Director of BancBoston Ventures, Inc., Ironwood Pharmaceuticals, Inc., Neurometrix, Microbia, NuGenesis Technologies Corp., and Syntonix Pharmaceuticals. She served as a Director of Critical Therapeutics Inc. since October 2003. Ms. George served as a Director of Hypnion, Inc. and Proteolix, Inc. She served as a Member of the Scientific Advisory Board for the Massachusetts Life Sciences Center. She featured on the Forbes Midas list. She has an MBA degree from Simmons College Graduate School of Management and a BS degree in Biology from the University of Maine.

Corporate Headquarters 485 Ramona Street Palo Alto, California 94301 United States Phone: 650-388-3676 Fax: 650-388-3675 Board Members Memberships Former Director Ironwood Pharmaceuticals, Inc. Former Director Hypnion, Inc. Director NuGenesis Technologies Corporation Director Hydra Biosciences, Inc. Director Acceleron Pharma, Inc. Director Onyx Therapeutics, Inc. Director Calithera Biosciences, Inc. Director Thrasos Innovation Inc. 2003-N/A Former Director, Chairman of Compensation Committee and Member of Audit Committee Critical Therapeutics Inc. 2005-Present Independent Director and Chairman of Compensation Committee Portola Pharmaceuticals, Inc. 2005-Present Director, Member of Compensation Committee and Member of Nominating & Corporate Governance Committee ZELTIQ Aesthetics, Inc. Education BS University of Maine MBA Simmons Graduate School of Business Management Other Affiliations Advanced Technology Ventures BancBoston Capital, Inc. BancBoston Ventures, Inc. Ironwood Pharmaceuticals, Inc. Hypnion, Inc. NuGenesis Technologies Corporation Critical Therapeutics Inc. Hydra Biosciences, Inc. University of Maine Portola Pharmaceuticals, Inc. Acceleron Pharma, Inc. Onyx Therapeutics, Inc. Simmons Graduate School of Business Management ZELTIQ Aesthetics, Inc. Calithera Biosciences, Inc. Thrasos Innovation Inc.

Annual Compensation There is no Annual Compensation data available. Stocks Options There is no Stock Options data available. Total Compensation There is no Total Compensation data available.

COMPETITOR COMPENSATION

There is no Competitor Compensation data available.