November 24, 2014 10:09 AM ET

Biotechnology

Company Overview of OpGen, Inc.

Company Overview

OpGen, Inc., a whole genome analysis company, engages in developing and commercializing genomic and DNA analysis systems and services worldwide. It offers Argus Optical Mapping System, a platform for automated and microbial whole genome analysis that brings comparative genomics, whole genome sequence assembly, and strain characterization into laboratory; and Argus whole genome mapping and genome builder software solution. The company also provides MapIt Optical Mapping Services as a commercial laboratory for specific microbial projects on a by-quotation basis for applications in the areas of clinical and food microbiology, epidemiology, pharmacology, manufacturing quality control, and applie...

708 Quince Orchard Road

Gaithersburg, MD 20878

United States

Founded in 2001

Phone:

301-869-9683

Fax:

301-869-9684

Key Executives for OpGen, Inc.

Chief Executive Officer and Director
Age: 52
Executive Chairman
Age: 57
Chief Financial Officer
Age: 57
Vice President of Business Development & Operations
Senior Vice President of Commercial Operations
Compensation as of Fiscal Year 2014.

OpGen, Inc. Key Developments

OpGen Launches First “Superbug” Molecular Screening Test to Identify Seven Critical Antibiotic Resistant Genes

OpGen announced that it has launched a new molecular-based test that can quickly and reliably identify patients at risk for harboring serious disease-causing microbes that can resist even the strongest antibiotics. The Acuitas MDRO Gene Test is a comprehensive molecular screening tool that can directly detect as many as seven genes from one patient sample, and will help hospitals and public health officials combat some of the most critical multi-drug resistant organisms (MDROs) threatening patients in healthcare facilities. Unlike current microbe detection methods based on growing cells in laboratory culture (a process that can take up to four days and can miss patients at risk for being colonized), the Acuitas test uses highly sensitive molecular technology to detect antibiotic resistant genes within 24 hours. It can distinguish specific genes that may aid in therapeutic guidance. Molecular technologies have been shown to have sensitivity greater than 95%, better assuring that at-risk patients are not missed. The Acuitas MDRO Gene Test is currently performed at the CLIA-certified OpGen Clinical Services Laboratory in Gaithersburg, Maryland. The Acuitas MDRO Gene Test uses DNA amplification and detection technology to detect genes associated with some of the world’s most deadly bacteria. Among these bacteria are carbapenem resistant enterobacteriaceae (CRE) containing KPC, NDM-1, and OXA-48 genes. They are resistant to nearly all antibiotics including carbapenems, a broad spectrum class of antibiotics considered to be the last resort for serious gram-negative bacterial infections. In critical care settings, death rates from KPC patients often exceed 50%. In 2013, The Centers for Disease Control (the CDC) identified CRE infection as an urgent public health threat requiring immediate and aggressive action.

OpGen, Inc. and Hitachi High-Technologies Corporation Enter into an Agreement to Develop Human Chromosome Mapping Analytical Service

OpGen, Inc. and Hitachi High-Technologies Corporation announced an agreement to develop a comprehensive human chromosome mapping analytical service for clinical research applications by a combination of OpGen's market-leading Whole Genome Mapping(TM) technology and Hitachi High-Technologies' and Hitachi group's cloud-based systems. This service will include bioinformatics tools to complete human genome sequence, and detect and analyze structural variations in human chromosomes. Under the terms of this agreement, Hitachi High-Technologies will fund development, and the companies will work together to combine the strengths of their proprietary technologies. OpGen's Whole Genome Mapping provides a unique view into structural variation in human chromosomes and offers a more accurate and complete analysis of the human genome than next generation sequencing data alone can provide. Many structural variations are associated with cancer, autism, Alzheimer's disease and many other cognitive disorders. This type of genetic information will enable development of new therapies, and eventually will empower the broader healthcare community to diagnose and guide treatment decisions based on a patient's genetic profile.

OpGen, Inc. Announces Partnership with Applied Maths to Provide Bioinformatics Analysis Software for Whole Genome Mapping

OpGen, Inc. announced the company has entered into a strategic collaboration with Applied Maths NV, to provide advanced software tools for microbial genomics and molecular strain typing. Under the agreement, Applied Maths has incorporated a Whole Genome Mapping module into the company's new BioNumerics 7 software suite, providing customers with seamless access to a new set of analytical tools for molecular typing and comparative genomics of microbial pathogens.

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