July 14, 2014 4:47 AM ET

Pharmaceuticals

Company Overview of Ascletis, Inc.

Company Overview

Ascletis, Inc., a specialty therapeutics company, discovers and develops treatments for cancer and infectious diseases. It provides ALN-VSP, a therapeutic comprising of siRNAs designed to target genes critical for the growth and development of cancer cells. The company has strategic partnerships with Alnylam Pharmaceuticals, Inc.; and Minsheng Pharma. Ascletis, Inc. was founded in 2011 and is based in Chapel Hill, North Carolina with operation sites in Hangzhou, China; and Research Triangle Park, North Carolina.

1002 Northridge Lane

Chapel Hill, NC 27514

United States

Founded in 2011

Phone:

919-928-5707

Key Executives for Ascletis, Inc.

Founder
Founder and Director
Chief Strategy Officer and Founding Advisor
Age: 64
Head of Business Development
Age: 50
Vice President of Research
Compensation as of Fiscal Year 2014.

Ascletis, Inc. Key Developments

Roche and Ascletis Enter Collaboration to Advance Treatment Options for Chinese Patients with Hepatitis C

Roche and Ascletis announced that they have entered into a collaboration to develop and commercialize Roche's investigational drug danoprevir in China for the treatment of Hepatitis-C Virus (HCV). It is estimated that over 10 million patients in China are chronically infected with HCV. The majority of these are genotype 1b, which has proven highly responsive to danoprevir. Roche and Ascletis are joining forces to develop a therapy with the potential to address a serious public health problem and to provide an effective new treatment option for Chinese patients with HCV. Under the terms of the agreement, Ascletis will fund and be responsible for the development, regulatory affairs and manufacturing of danoprevir in greater China, including Taiwan, Hong Kong and Macau and receive payments upon reaching certain development and commercial milestones from Roche. Ascletis and Roche will collaborate for the clinical development and the commercialization. The contract also involves royalties.

Ascletis, Inc. Presents at Fifth Annual ChinaBio(R) Partnering Forum 2013, May-29-2013 through May-30-2013

Ascletis, Inc. Presents at Fifth Annual ChinaBio(R) Partnering Forum 2013, May-29-2013 through May-30-2013. Venue: Shangri-La Hotel, 29 Zizhuyuan Road, Beijing 100089, China. Presentation Date & Speakers: May-29-2013, Jinzi J. Wu, PhD, Founder, President and CEO. May-30-2013, Jinzi J. Wu, PhD, Founder, President and CEO.

Roche and Ascletis Enter Collaboration to Advance Treatment Options for Chinese Patients with Hepatitis C

Roche and Ascletis announced that they have entered into a collaboration to develop and commercialize Roche’s investigational drug danoprevir in China for the treatment of Hepatitis-C Virus (HCV). It is estimated that over 10 million patients in China are chronically infected with HCV. The majority of these are genotype 1b, which has proven highly responsive to danoprevir. Roche and Ascletis are joining forces to develop a therapy with the potential to address a serious public health problem and to provide an effective new treatment option for Chinese patients with HCV. Under the terms of the agreement, Ascletis will fund and be responsible for the development, regulatory affairs and manufacturing of danoprevir in greater China, including Taiwan, Hong Kong and Macau and receive payments upon reaching certain development and commercial milestones from Roche. Ascletis and Roche will collaborate for the clinical development and the commercialization. The contract also involves royalties.

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