September 15, 2014 6:12 AM ET

Biotechnology

Company Overview of Chroma Therapeutics Ltd.

Company Overview

Chroma Therapeutics Ltd. operates as a biotechnology company. The company focuses on chromatin biology and novel drug accumulation approaches to discover and develop cancer and inflammation treatments, and small molecule drugs. The company was incorporated in 2000 and is based in Abingdon, United Kingdom.

93 Milton Park

Abingdon,  OX14 4RY

United Kingdom

Founded in 2000

Phone:

44 1235 829120

Fax:

44 1235 829125

Key Executives for Chroma Therapeutics Ltd.

Chief Executive Officer and Director
Age: 45
Founder and Member of Scientific Advisory Board
Age: 56
Founder and Member of Scientific Advisory Board
Chief Medical Officer
Compensation as of Fiscal Year 2014.

Chroma Therapeutics Ltd. Key Developments

Cell Therapeutics, Inc. and Chroma Therapeutics Ltd. Announces Results from the Opal Phase 2 Study of Tosedostat in Elderly Patients with Relapsed or Refractory Acute Myeloid Leukemia

Cell Therapeutics, Inc. and Chroma Therapeutics Ltd. announced that Lancet Oncology has published results from the OPAL Phase 2 study of tosedostat in elderly patients with relapsed or refractory acute myeloid leukemia (AML). Tosedostat is an oral aminopeptidase inhibitor which has been shown to deprive tumor cells of the amino acid building blocks they need to make proteins necessary for tumor cell survival. The lead author was Dr. Jorge Cortes, Professor of Medicine and Internist, Department of Leukemia, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center in Houston, Texas. The trial showed that once-daily oral tosedostat resulted in a disease control rate of 51%. Subset analyses suggested the greatest benefit occurred in the difficult-to-treat patients with prior myelodysplastic syndrome (MDS) or those that had received prior hypomethylating therapy (HMA). Adverse events were mild, predictable and manageable.

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