September 22, 2014 4:32 AM ET


Company Overview of Astex Therapeutics Limited

Company Overview

Astex Therapeutics Limited discovers and develops molecularly-targeted oncology and virology drugs based on its pyramid drug discovery engine. Its products include Dacogen—Hypomethylator, a DNA hypomethylating agents for the treatment of myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML); and AT13387—Hsp90 inhibitor, a molecular chaperone that stabilizes and prevents the breakdown of cancer-forming/oncogenic proteins. The company also provides SGI-110—DNMT inhibitor, a DNA-hypomethyating agent that restores silenced tumor suppressor gene expression in cancer cells by reversal of DNA methylation; Amuvatinib (MP-470), a tyrosine kinase inhibitor that targets cancer cells by disru...

436 Cambridge Science Park

Cambridge,  CB4 0QA

United Kingdom

Founded in 1999

74 Employees


44 12 2322 6200


44 12 2322 6201

Key Executives for Astex Therapeutics Limited

Age: 51
Co-Founder and Member of Scientific Advisory Board
Age: 71
Vice President of Finance & Administration and Company Secretary
Senior Vice President of Intellectual Property
Compensation as of Fiscal Year 2014.

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