October 02, 2014 11:27 AM ET


Company Overview of Parion Sciences, Inc.

Company Overview

Parion Sciences, Inc., a pharmaceutical company, engages in the discovery and development of new treatments for serious diseases in multiple therapeutic areas. The company primarily focuses on developing therapeutic agents for pulmonary diseases, including cystic fibrosis, chronic obstructive pulmonary disorder, and bronchiectasis. It develops epithelial sodium channel blockers that are used for the treatment of diseases associated with lung, mouth, nose, and the gastrointestinal tract. The company also develops an oral rinse for the relief of chronic dry mouth; and compounds for patients suffering from dry eyes. It was formerly known as CYFI, Inc. and changed its name to Parion Sciences, In...

2800 Meridian Parkway

Suite 195

Durham, NC 27713

United States

Founded in 1999





Key Executives for Parion Sciences, Inc.

Age: 69
Co-Founder and Co-Chairman
Chief Operating Officer
Age: 49
Senior Director of Clinical & Regulatory Operations
Compensation as of Fiscal Year 2014.

Parion Sciences, Inc. Key Developments

Parion Sciences Announces Exclusive Option Agreement for the Development and Commercialization of P-321 in Ophthalmology in Certain Asian Territories

Parion Sciences, Inc. announced that Parion and Santen Pharmaceutical Co. Ltd. have entered into the "OPTION, LICENSE AND DEVELOPMENT AGREEMENT", an exclusive option agreement for the development and commercialization of P-321 for dry eye disease in certain Asian territories. On May 1, 2014 Parion announced FDA Acceptance of the Investigational New Drug Application for clinical testing of P-321 Ophthalmic Solution for the Treatment of Dry Eye Disease. Parion plans to initiate a Phase 1/2a clinical trial in patients suffering from dry eye disease in July, 2014 in the United States. Under the terms of agreement, Santen will make an undisclosed option payment to secure certain rights to P-321 and to support the upcoming Phase 1/2a clinical trial. Should Santen elect to exercise their option, Santen will have responsibility for all clinical, regulatory, and commercial activity for the ophthalmic use of P-321 in the agreed Asian territories. Parion retains all rights to develop and commercialize P-321 in the rest of the world, including North America and Europe.

Parion Sciences Announces Executive Changes

Parion Sciences announced senior leadership and organizational changes. The changes include the following: Paul Boucher has been promoted to President and will lead the executive management team, business development and provide overall corporate direction. Paul previously served as Vice-President of Finance & Business at Parion. Joe Schachle has been appointed as Chief Operating Officer (COO) and will be responsible for corporate strategy, commercial operations, and corporate operations. Joe joined Parion from Grifols where he served as Head of Global Marketing Operations. Anita Woodring has been appointed as Senior Director of Clinical & Regulatory Operations. Anita is joining Parion from Research Triangle Institute (RTI) where she served as Regulatory Project Leader. These changes are intended to support the growth plans for the organization based on the initiation of trials across 3 clinical programs and increased efforts in early stage research projects.

Parion Sciences Receives FDA Acceptance of the Investigational New Drug Application for Clinical Testing of P-321 Ophthalmic Solution for the Treatment of Dry Eye Disease

Parion Sciences announced that it has received acceptance from the U.S. Food and Drug Administration (FDA) of its Investigational New Drug (IND) application for P-321 Ophthalmic Solution for the treatment of dry eye disease. Preclinical data that supported this approval will be presented in a poster session at the Association for Research in Vision and Ophthalmology Annual Meeting (ARVO) on May 6, 2014, in Orlando, Fla. P-321 is the result of a comprehensive research effort to develop a potent ENaC inhibitor with unique pharmacokinetic and pharmacodynamics characteristics designed for topical ocular administration, metabolic stability and limited systemic exposure. Parion Sciences has completed all the preclinical safety and mechanistic studies required to initiate clinical studies in humans.

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