August 27, 2014 7:24 PM ET

Biotechnology

Company Overview of Allos Therapeutics, Inc.

Company Overview

Allos Therapeutics, Inc., a biopharmaceutical company, engages in the development and commercialization of anti-cancer therapeutics. It focuses on the development and commercialization of FOLOTYN (pralatrexate injection), a folate analogue metabolic inhibitor. FOLOTYN is approved in the United States for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). It is also developing FOLOTYN in other hematologic malignancies. The company has a strategic collaboration agreement with Mundipharma International Corporation Limited (Mundipharma) to co-develop FOLOTYN. Allos Therapeutics, Inc. has commercialization rights for FOLOTYN in the United States and Canada; a...

11080 CirclePoint Road

Suite 200

Westminster, CO 80020

United States

Founded in 1992

Phone:

303-426-6262

Fax:

303-426-4731

Key Executives for Allos Therapeutics, Inc.

President and Secretary
Chief Financial Officer and Treasurer
Senior Vice President
Age: 44
Chief Medical Officer and Executive Vice President
Age: 49
Senior Vice President of Corporate Development
Age: 48
Compensation as of Fiscal Year 2014.

Allos Therapeutics, Inc. Key Developments

Allos Therapeutics, Inc. Enters into an Amended and Restated License, Development and Commercialization Agreement with Mundipharma International Limited

On May 29, 2013, Allos Therapeutics, Inc. entered into an Amended and Restated License, Development and Commercialization Agreement by and between the company and Mundipharma International Limited, which amended and restated a May 2011 agreement between the parties. The Amended License Agreement provides for a strategic collaboration between the parties related to the development of FOLOTYN. The company received a $50 million upfront payment upon execution of the May 2011 agreement. Under the Amended License Agreement, the company will receive $7 million as reimbursement of research and development costs incurred by the company through the date of the Amended License Agreement. Additionally, the company will be eligible to receive potential regulatory milestone payments of up to an aggregate of approximately $16 million based on approvals of FOLOTYN for the treatment of PTCL in a specified patient population in Japan, China, Latin America and Australia, respectively, commercial-progress based on initial sales in Japan and overall sales-dependent milestones of up to $107 million and tiered double digit royalties on net sales in the Mundipharma territories. Mundipharma is responsible for 40% of joint development costs incurred by the parties through May 31, 2013 related to certain FOLOTYN studies, with each party accountable for its future cost of conducting studies for which it is obligated and the allocation of responsibility for new studies to be agreed upon by the parties. Pursuant to the terms of the Amended License Agreement, the company will gain the commercialization rights to FOLOTYN in Europe and Turkey, with an option for Switzerland, while Mundipharma will retain exclusive rights to commercialize FOLOTYN in the Mundipharma territories, including Asia and Latin America. The Amended License Agreement will remain in effect, on a country-by-country basis, until the expiration of Mundipharma's obligation to pay royalties on net sales of the subject products in such country. Mundipharma may terminate the Agreement at its election upon 90 days' notice to the Company, or immediately in the event that the company's license agreement dated December 23, 2002, as amended, with SRI International, Sloan-Kettering Institute for Cancer Research and Southern Research Institute is terminated without Mundipharma's consent. The company may terminate the Agreement at its election immediately with respect to the territory of Japan only, in the event that Mundipharma does not achieve certain milestones in Japan. Additionally, either party may terminate the Agreement for an uncured material breach by the other party. Concurrently with the execution of the Amended License Agreement, the company and Mundipharma Medical Company entered into an Amended and Restated Supply Agreement, which amended and restated a May 2011 agreement between the parties. Pursuant to the terms of the Amended Supply Agreement, subject to certain exceptions, MMC agreed to purchase and the company agreed to supply MMC's clinical and commercial requirements of FOLOTYN. The term of the Amended Supply Agreement is concurrent with the term of the Amended License Agreement and may be terminated by either party for an uncured material breach by the other party or upon certain bankruptcy proceedings involving the other party.

Allos Therapeutics, Inc.(NasdaqGS:ALTH) dropped from NASDAQ Composite Index

Allos Therapeutics, Inc. will be removed from NASDAQ Composite Index

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