December 22, 2014 7:17 PM ET


Company Overview of 3-V Biosciences, Inc.

Company Overview

3-V Biosciences, Inc. operates as a biopharmaceutical company that discovers and develops therapeutics for the treatment of oncology and infectious diseases. The company offers a TVB-2640, a fatty acid synthase inhibitor that blocks tumor cell signaling pathways and induces tumor cell apoptosis. It also focuses on developing antiviral therapeutic candidates for respiratory syncytial virus, cytomegalovirus, and other human pathogens. The company was incorporated in 2006 and is based in Menlo Park, California.

1050 Hamilton Court

Menlo Park, CA 94025

United States

Founded in 2006



Key Executives for 3-V Biosciences, Inc.

Chief Executive Officer
Executive Chairman
Age: 49
Chief Medical Officer
Compensation as of Fiscal Year 2014.

3-V Biosciences, Inc. Key Developments

3-V Biosciences, Inc. Presents at Oppenheimer 25th Annual Healthcare Conference, Dec-11-2014 09:10 AM

3-V Biosciences, Inc. Presents at Oppenheimer 25th Annual Healthcare Conference, Dec-11-2014 09:10 AM. Venue: The Crowne Plaza Hotel, New York, New York, United States. Speakers: Merdad V. Parsey, Chief Executive Officer, President and Director.

3-V Biosciences, Inc. Commences Patient Dosing in Phase 1 Clinical Study of FASN Inhibitor TVB-2640 in Patients with Advanced Solid Tumors

3-V Biosciences, Inc. announced the recent initiation of a Phase 1 clinical study of TVB-2640 in patients with advanced solid tumors. TVB-2640 is an oral, proprietary fatty acid synthase (FASN) inhibitor being evaluated for the treatment of solid tumors. FASN is an enzyme responsible for the synthesis of palmitic acid and has a key role in tumor metabolism, lipid signaling and tumor cell survival. The Phase 1 open-label, dose-escalation trial will enroll patients with advanced solid tumors whose cancer has become refractory to standard therapy, and for whom no useful treatment exists. Patients will receive TVB-2640 once daily for 21 days. The primary endpoint for the Phase 1 study is the identification of any dose-limiting toxicities and the establishment of a maximum-tolerated dose (MTD) for oral TVB-2640. Secondary and exploratory endpoints include safety, pharmacokinetics, and initial signs of efficacy and evidence of FASN biomarker activity. FASN over-expression is associated with aggressive disease and poor prognosis in a number of cancers. In a series of preclinical studies, 3-V's FASN inhibitors demonstrated potent activity against multiple tumor types, including breast, lung, pancreatic, ovarian and colon cancers. FASN inhibition reduced cell proliferation and induced apoptosis (cell death) in a dose-dependent manner and single-agent FASN inhibition both blocked tumor growth and resulted in significant tumor regression in patient-derived xenografts. In addition, 3-V has demonstrated potential synergy of its FASN inhibitors with cytotoxic agents.

3-V Biosciences, Inc. Names William McCulloch as Chief Medical Officer

3-V Biosciences, Inc. announced that William McCulloch, MB, ChB, FRCP, FFPM has joined the company as Chief Medical Officer. Dr. McCulloch brings nearly three decades of senior research and development experience to 3-V, including an extensive preclinical and clinical development background in oncology. Dr. McCulloch will be responsible for 3-V's clinical, medical affairs and regulatory functions, overseeing strategy and implementation for the advancement of 3-V's pipeline of proprietary therapeutic candidates. Dr. McCulloch previously served as Chief Medical Officer at Gloucester Pharmaceuticals, Inc.

Similar Private Companies By Industry

Company Name Region
Tomtec, Inc. United States
Phytosphere Systems, LLC United States
Lumena Pharmaceuticals Inc. United States
Epigenomics, Inc. United States
Micromet, Inc. United States

Recent Private Companies Transactions

No transactions available in the past 12 months.

Stock Quotes

Market data is delayed at least 15 minutes.

Company Lookup

Most Searched Private Companies

Company Name Geographic Region
Bertelsmann AG Europe
Lawyers Committee for Civil Rights Under Law United States
NYC2012, Inc. United States
Rush University United States
Citizens Budget Commission United States

Sponsored Financial Commentaries

Sponsored Links

Report Data Issue

To contact 3-V Biosciences, Inc., please visit Company data is provided by Capital IQ. Please use this form to report any data issues.

Please enter your information in the following field(s):
Update Needed*

All data changes require verification from public sources. Please include the correct value or values and a source where we can verify.

Your requested update has been submitted

Our data partners will research the update request and update the information on this page if necessary. Research and follow-up could take several weeks. If you have questions, you can contact them at