December 18, 2014 3:59 AM ET


Company Overview of Oligomerix, Inc.

Company Overview

Oligomerix, Inc. operates as biopharmaceutical companyand develops drugs for Alzheimer’s disease and other neurodegenerative disorders. The company was founded in 2006 and is based in New York, New York.

Audubon Business and Technology Center

Columbia University Medical Center

3960 Broadway

Suite 440C

New York, NY 10032

United States

Founded in 2006





Key Executives for Oligomerix, Inc.

Chief Executive Officer and President
Chief Commercial Officer and Director
Senior Director of Chemistry
Compensation as of Fiscal Year 2014.

Oligomerix, Inc. Key Developments

Oligomerix, Inc. Announces the Relocation of Corporate Headquarters

Oligomerix, Inc. announced the relocation of its corporate headquarters to Valhalla, NY as of January 15, 2014 and expanded lease agreement for additional laboratory space at New York Medical College.

Taconic and Oligomerix to Collaborate on Tau Mouse Model Characterization for Use in Alzheimer's Disease Research

Taconic and Oligomerix, Inc. announced a collaboration to evaluate the utility of the Taconic tau mouse model (also known as the JNPL3 mouse) as a tool for pre-clinical testing of compounds for Alzheimer's disease. Used extensively in neurodegenerative disease research, the tau mouse model is part of the Taconic Transgenic Models(TM) (TTM(TM)) portfolio of in-licensed transgenic models available off-the-shelf in typical study quantities. For years Alzheimer's disease was believed to be caused by the toxic buildup of the amyloid beta protein. Most of the therapeutic methods under development have aimed to cut amyloid levels in order to prevent or delay onset of the disease. To date, all completed Phase III drug development programs based on the amyloid hypothesis have failed to meet their clinical endpoints. Oligomerix's work focuses on an alternate hypothesis that is rapidly advancing in the scientific community: that the accumulation of the tau protein, specifically tau oligomerization, is highly correlated with Alzheimer's disease progression and therefore an appropriate target for the development of disease-modifying therapeutics. Oligomerix will test this hypothesis using Taconic's tau mouse model that carries the transgene for the human mutation of the microtubule-associated protein -- tau. The Taconic tau model has been well-characterized for behavioral and motor disturbances related to the development of neurofibrillary tangles that are pathological hallmarks of Alzheimer's disease. Oligomerix will employ Taconic's model to develop assays to detect tau oligomers and evaluate the model's utility in preclinical testing using reference compounds already screened in cell assays.

Oligomerix, Inc. Appoints James Hendrix as Senior Director of Chemistry

Oligomerix, Inc. announced that James Hendrix, Ph.D., has been appointed Senior Director of Chemistry of the company. Dr. Hendrix has more than 20 years of pharmaceutical research experience, predominantly in the area of neuroscience research, including AD. His focus has primarily been on the discovery of drug candidates, having successfully led teams that have advanced many compounds into clinical and preclinical development. Before being appointed senior director for Sanofi-Aventis, Dr. Hendrix served as director of medicinal chemistry with a focus on central nervous system (CNS) disorders. In this position, Dr. Hendrix managed 30 medicinal chemists focused on drug discovery for CNS targets and was a member of the company's global CNS Management Board.

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