August 01, 2014 2:45 AM ET

Pharmaceuticals

Company Overview of Aragon Pharmaceuticals, Inc.

Company Overview

Aragon Pharmaceuticals, Inc. develops medicines for the treatment of hormonally-driven cancers such as prostate and breast cancer. It develops ARN-509, a compound for the treatment of castration-resistant prostate cancer. It also develops selective androgen receptor degraders and selective estrogen receptor degraders that prevent cancer growth by inhibiting hormone action on the receptor and inducing receptor degradation; and ARN-810, an oral selective estrogen receptor degrader for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer in post-menopausal women. The company was founded in 2009 and is based in San Diego, California. As of August 19, 2013, Ara...

12780 El Camino Real

Suite 301

San Diego, CA 92130

United States

Founded in 2009

Phone:

858-369-7600

Fax:

858-369-7650

Key Executives for Aragon Pharmaceuticals, Inc.

Co-Founder and Scientific Advisor
Age: 55
Chief Medical Officer
Age: 52
Chief Business Officer
Vice President of Finance
Age: 41
Compensation as of Fiscal Year 2014.

Aragon Pharmaceuticals, Inc. Key Developments

Aragon Pharmaceuticals, Inc. Presents at Jefferies 2013 Global Healthcare Conference, Jun-05-2013 08:00 AM

Aragon Pharmaceuticals, Inc. Presents at Jefferies 2013 Global Healthcare Conference, Jun-05-2013 08:00 AM. Venue: Grand Hyatt Hotel, 109 East 42nd Street at Grand Central, New York, New York, United States. Speakers: Paul B. Cleveland, Chief Financial Officer and Executive Vice President of Corporate Strategy.

Aragon Pharmaceuticals, Inc. Announces First Patient Dosed in Phase I Study of ARN-810 in Estrogen Receptor Positive Breast Cancer

Aragon Pharmaceuticals, Inc. announced that the first patient has been dosed in a Phase I clinical study of ARN-810, an oral selective estrogen receptor degrader (SERD), for the treatment of locally advanced or metastatic estrogen receptor positive breast cancer in post-menopausal women. Approximately 70% of breast cancers are dependent on estrogen for growth and survival. Current treatment generally involves antihormonal therapies, such as tamoxifen or aromatase inhibitors. Although these therapies are initially effective, acquired resistance is common, leading to disease progression. ARN-810 is a potent, orally bioavailable nonsteroidal agent, which functions by binding to the estrogen receptor, inducing a conformational change resulting in the degradation of the receptor. As such, its novel profile represents a new treatment that may circumvent resistance seen in traditional therapies. The Phase 1 dose escalation study is designed to assess safety and tolerability of ARN-810. The study will be conducted at Vanderbilt University, Mass General Hospital and Memorial Sloan-Kettering Cancer Center.

Aragon Pharmaceuticals, Inc. Appoints Paul Cleveland as Chief Financial Officer and Executive Vice President, Corporate Strategy

Aragon Pharmaceuticals, Inc. announced that Paul Cleveland has joined the company as Chief Financial Officer and Executive Vice President, Corporate Strategy. In this role, Mr. Cleveland will be responsible for the company's finance, legal, investor relations and business development matters. Prior to Aragon, Mr. Cleveland spent two years as a General Partner and Chief Operating Officer at Mohr Davidow Ventures. Previously, he spent five years at Affymax Inc., where he served as Executive Vice President, Corporate Development and Chief Financial Officer, leading the Company through its successful public offering in 2006. He also brings to Aragon 15 years of experience as a practicing attorney, most recently as a Partner within the Corporate Group at Cooley Godward in Palo Alto, CA. Mr. Cleveland has served as a member of the Board of Directors of three biotechnology companies, and currently serves as a member of the Board of Sangamo Biosciences, Inc.

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