April 17, 2014 6:59 PM ET

Biotechnology

Company Overview of Bicycle Therapeutics Limited

Company Overview

Bicycle Therapeutics Limited, a biotechnology company, develops a technology platform for the identification and optimization of chemically constrained cyclic peptides. It offers its technology platform for the creation of biotherapeutics that combine the features of small molecules and biopharmaceuticals to create drugs. The company was founded in 2009 and is based in Cambridge, United Kingdom.

Meditrina Building

Babraham Research Campus

Cambridge,  CB22 3AT

United Kingdom

Founded in 2009

Phone:

44 1223 497 390

Key Executives for Bicycle Therapeutics Limited

Chief Executive Officer and Director
Scientific Founder
Scientific Founder and Director
Age: 62
Chief Scientific Officer
Compensation as of Fiscal Year 2013.

Bicycle Therapeutics Limited Key Developments

ThromboGenics and Bicycle Therapeutics Seal Cooperation Agreement on Novel Ophthalmic Medicines

ThromboGenics announced that it has entered into a collaboration and licence agreement with Bicycle Therapeutics for the development and commercialisation of novel drugs that inhibit a particular target for the treatment of ophthalmic diseases, such as diabetic macular oedema/edema (DME). In particular, ThromboGenics intends to use the Bicycle Therapeutics bicyclic peptides for developing therapeutics that inhibit a target involved in vascular permeability. The companies will be collaborating on the preclinical development of these bicyclic peptide inhibitors; while ThromboGenics has an exclusive licence to take up the clinical development and commercialisation of identified drug candidates. In its turn, Bicycle will receive an upfront payment as well as development and regulatory milestone payments, and sales royalties, the details of which have not been disclosed. Significance: The selective inhibition of a target involved in vascular permeability is a new approach that could potentially help improve the DME treatment, a condition that affects around 30% of all patients who have suffered from diabetes for over 20 years and are at risk of developing the condition.

Bicycle Therapeutics Limited Presents at EBD Group's 7th Annual BIO-Europe Spring Conference 2013, Mar-11-2013

Bicycle Therapeutics Limited Presents at EBD Group's 7th Annual BIO-Europe Spring Conference 2013, Mar-11-2013 . Venue: Centre Covencions International Barcelona, Plaça de Willy Brandt, 11-14, 08019 Barcelona, Spain.

Bicycle Therapeutics Limited Presents at Sachs Associates Ltd.'s 12th Annual Biotech in Europe Investor Forum, Oct-01-2012 through Oct-02-2012

Bicycle Therapeutics Limited Presents at Sachs Associates Ltd.'s 12th Annual Biotech in Europe Investor Forum, Oct-01-2012 through Oct-02-2012. Venue: Hilton Zurich Airport Hotel, Zurich, Zurich, Switzerland. Presentation Date & Speakers: Oct-01-2012, Rolf H. Guenther, Chief Executive Officer and Director.

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