Company Overview of Xcellerex, Inc.
Xcellerex, Inc. develops biomolecule manufacturing technologies and platforms. Its products and services include FlexFactory, a bioprocess manufacturing platform that handles the production of bioproducts, such as vaccines, yeast, and insulins; XDR single-use bioreactors, which are integrated systems for GMP clinical and commercial production; XDM QUAD single-use mixing systems that are used in the preparation of buffers, media, product, and other process fluids; and XDA disposable assembly, which include gas filters, agitation system components, sparge components, probes, ports, pressure sensors, sampling ports, and gas and liquid transfer tubes. The company also provides PDMax, a high thro...
170 Locke Drive
Marlborough, MA 01752-7217
Founded in 2002
Key Executives for Xcellerex, Inc.
Founder and Chief Technology Officer
Senior Director of Global Marketing & Product Management
Senior Director of Products & Sales
Compensation as of Fiscal Year 2013.
Xcellerex, Inc. Key Developments
Xcellerex Introduces XDR-10 Single-Use Bioreactor for Benchtop Use
Jun 15 12
Xcellerex, Inc. introduced its XDR(TM)-10 single-use bioreactor designed for benchtop use. The XDR-10 allows smooth scale-up to full production and is ideal for GMP clinical and commercial manufacture of biotherapeutics, vaccines, and other biologics. The new system is the industry's first and only bag-type single-use bioreactor flexible enough to handle volumes from 4 L to 10 L. It is available in single-, twin-, triplet-, and quad-vessel configurations. The new bioreactor joins Xcellerex's existing line of fully-integrated, fully-characterized systems available with working volumes of 50, 200, 500, 1,000 and 2,000 liters -- and features the same fluid contact materials, fluid dynamics, and control strategies. It also integrates with Xcellerex's revolutionary FlexFactory(R) biomanufacturing platform. The XDR-10's reliable, predictable results greatly reduce risks and times in scaling from benchtop pilot to production. Features include: Superior sparging flexibility for unmatched adaptability to the broadest range of cell lines. A low shear, high input-power impeller provides gentle, efficient mixing for sensitive cells or media. Optimized impeller position maximizes volume range and turndown ratio. Industrial-grade automation ensures process performance and consistent data management. Perfect for process development, small-scale production, seed train culture, or process troubleshooting. The XDR-10 was designed with extensive customer input to execute the most critical biopharmaceutical tasks in a benchtop form factor. It can function as a production vessel in its own right, or become a scale-down tool or satellite platform (with multiple-vessel configurations available) for larger projects to be continued in larger bioreactors. The XDR-10 handles the industry's toughest challenges in process development -- to perform as a small-scale production vessel and work as an ideal vehicle for seed-train culture. In any application, the XDR-10's power and flexibility minimize the number of required runs -- to save time, work, and costs.
Xcellerex, Inc. Launches Intelligent Single-Use Mixing Systems for Single-Use Biomanufacturing
May 2 12
Xcellerex, Inc. has launched its XDUO(TM) Quad(TM) single-use mixing system supporting single-use biomanufacturing in upstream and downstream mixing applications and unit operations. The XDUO mixer represents the next-generation advancement in automated single-use solutions for the mixing of buffer, media, product, and other process fluids. An evolution of the original XDM(TM) system, the XDUO mixer enables unparalleled performance by adding new features and onboard instrumentation to support the application needs of the GMP manufacturing environment. The XDUO mixer integrates with existing biomanufacturing production lines as well as with the Xcellerex FlexFactory(R), a modular biomanufacturing platform that leverages single-use technology and advanced process automation. The FlexFactory flexible platform enables biomanufacturers to accelerate their deployment of new manufacturing capacity while lowering risk, decreasing time to market, and reducing capital costs. The XDUO single-use mixing system is the first mixer available with all instrumentation and automation features integrated as a stand-alone single-use mixing platform. The instrument panel includes a Siemens S7 1200 PLC, analog I/O cards, a 4-port switch, and a 4-inch monochrome HMI display. The instrument panel can be equipped with pH and conductivity transmitters, weight measurement, temperature monitoring, temperature control, and onboard pumps to support automated titration applications such as pH adjustment and viral inactivation. The XDUO system is also capable of both local and remote operation, data trending, and capture for batch record requirements in GMP manufacturing suites in data historian platforms, so it's ideal for supporting downstream unit operations in a single-use platform.
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