Last €105.30 EUR
Change Today -0.321 / -0.30%
Volume 2.6K
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As of 6:11 AM 08/29/14 All times are local (Market data is delayed by at least 15 minutes).

amgen inc (AMG) Snapshot

Open
€105.07
Previous Close
€105.62
Day High
€105.66
Day Low
€104.65
52 Week High
08/28/14 - €105.67
52 Week Low
10/10/13 - €78.31
Market Cap
80.0B
Average Volume 10 Days
3.7K
EPS TTM
--
Shares Outstanding
759.6M
EX-Date
08/12/14
P/E TM
--
Dividend
€2.41
Dividend Yield
1.61%
Current Stock Chart for AMGEN INC (AMG)

amgen inc (AMG) Details

Amgen Inc., a biotechnology company, discovers, develops, manufactures, and delivers human therapeutics in the areas of oncology, hematology, inflammation, bone health, nephrology, cardiovascular, and general medicine worldwide. Its principal products include Neulasta, a pegylated protein for the treatment of chemotherapy-induced febrile neutropenia; NEUPOGEN, a recombinant-methionyl human granulocyte colony-stimulating factor for treating the patients with non-myeloid malignancies; and Enbrel for the treatment of rheumatoid arthritis, plaque psoriasis, and psoriatic arthritis in adult patients. The company’s principal products also comprise Aranesp and EPOGEN erythropoiesis-stimulating agents for the treatment of anemia and dialysis; XGEVA and Prolia for the prevention of skeletal-related events and treatment of postmenopausal women with osteoporosis; and Sensipar/Mimpara products for use in the treatment of secondary hyperparathyroidism in CKD patients on dialysis. Its other marketed products include Nplate, a thrombopoietic compound; and Vectibix, a human monoclonal antibody. The company’s products in phase 3 clinical trial comprise Evolocumab, a human monoclonal antibody used for the treatment for dyslipidemia; Talimogene Laherparepvec for the treatment of unresected stage IIIB, IIIC, or IV melanoma; and Trebananib for the treatment of ovarian cancer. Its other product in development stage includes Ivabradine, an oral drug for chronic heart failure and stable angina in patients with elevated heart rates. The company markets its products to healthcare providers, including physicians or their clinics, dialysis centers, hospitals, and pharmacies; consumers; and pharmaceutical wholesale distributors. It has collaborative arrangements with Pfizer Inc.; Glaxo Group Limited; AstraZeneca Plc.; Takeda Pharmaceutical Company Limited; UCB; and Bayer HealthCare Pharmaceuticals Inc. Amgen Inc. was founded in 1980 and is headquartered in Thousand Oaks, California.

20,000 Employees
Last Reported Date: 02/24/14
Founded in 1980

amgen inc (AMG) Top Compensated Officers

Chairman, Chief Executive Officer, President,...
Total Annual Compensation: $1.5M
Executive Vice President of Operations
Total Annual Compensation: $1.1M
Executive Vice President of Global Commercial...
Total Annual Compensation: $1.0M
Executive Vice President of Research & Develo...
Total Annual Compensation: $896.5K
Senior Vice President, General Counsel and Se...
Total Annual Compensation: $845.9K
Compensation as of Fiscal Year 2013.

amgen inc (AMG) Key Developments

FDA Grants Amgen Priority Review Designation for Ivabradine for the Treatment of Chronic Heart Failure

Amgen announced the U.S. Food and Drug Administration (FDA) has granted priority review designation for ivabradine for the treatment of chronic heart failure (HF). Ivabradine is an oral drug that inhibits the I(f) current (funny current) in the sinoatrial node, the body's cardiac pacemaker. Ivabradine works to slow the heart rate without negative effects on myocardial contractility or ventricular repolarization. Heart failure is a common condition that affects approximately 26 million worldwide, including approximately 5.1 million people in the U.S. The New Drug Application (NDA) is based on global clinical trial data from the Phase 3 SHIFT (Systolic Heart failure treatment with the I(f) inhibitor ivabradine Trial) study, a large, multi-center, randomized, double-blind, placebo-controlled, outcomes trial. The pivotal SHIFT study compared ivabradine to placebo on top of standard-of-care therapies, including beta-blockers, in more than 6,500 patients in sinus rhythm with reduced left ventricular function and heart rate >70 beats per minute (bpm). Priority review designation is assigned to applications for drugs that treat serious conditions and would, if approved, provide significant improvements in the safety or effectiveness of the treatment, diagnosis, or prevention of serious conditions compared to available therapies. A priority review designation will set a goal date for taking action on an application within six months of receipt.

Amgen Appoints Elliott M. Levy as Senior Vice President, Global Development, Effective September 8, 2014

Amgen announced that Elliott M. Levy, M.D., has been named senior vice president, Global Development, effective Sept. 8, 2014. Levy comes to Amgen from Bristol-Myers Squibb (BMS), where he most recently served as senior vice president and head, Specialty Development.

Amgen Announces Second Placebo-Controlled Phase 3 Study

Amgen announced that second placebo-controlled Phase 3 study evaluating AMG 416 for the treatment of secondary hyperparathyroidism (SHPT) in patients with chronic kidney disease (CKD), receiving hemodialysis, met its primary and all secondary endpoints. The primary endpoint was the proportion of patients with > 30% reduction from baseline in parathyroid hormone (PTH) levels during an Efficacy Assessment Phase (EAP) defined as the period between weeks 20 and 27. These results follow the recent announcement of positive data from a prior placebo-controlled Phase 3 study of AMG 416 which was similar in design and size. In the AMG 416 group, 74.0% of patients achieved a > 30% reduction from baseline in PTH compared with 8.3% in the placebo arm, a statistically significant result. Both of these secondary endpoint results were statistically significant. Treatment-emergent adverse events (TEAEs) were reported in 91.6 and 78.7% of patients who received AMG 416 and placebo, respectively. TEAEs that were reported in > 10% of patients who received AMG 416 included (AMG 416 vs. placebo, respectively): blood calcium decreased (61.0 and 8.3%), nausea (12.4 and 5.1%), muscle spasms (12.0 and 7.1%) and vomiting (10.4 and 7.1%). TEAEs of hypocalcemia (symptomatic) were reported in 7.2% of patients who received AMG 416 versus 0.4% in the placebo group. Serious adverse events (SAEs) were reported in 27.1 and 30.7% of patients who received AMG 416 and placebo, respectively. This was a 26-week, randomized, double-blind, placebo-controlled study (study number 20120229) that evaluated the efficacy and safety of AMG 416 for the treatment of SHPT in 508 patients with CKD receiving hemodialysis. Patients received AMG 416 or placebo three times per week by intravenous injection with each hemodialysis treatment. Doses ranged from a minimum of 2.5 mg to a maximum of 15 mg. Patients also received standard of care which could include calcium supplements, vitamin D sterols and phosphate binders, if prescribed by the individual physician.

 

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AMG Competitors

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Company Last Change
AbbVie Inc $55.60 USD -0.10
AstraZeneca PLC 4,570 GBp +90.50
Bristol-Myers Squibb Co $50.54 USD +0.29
Eli Lilly & Co $63.11 USD +0.11
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AMG

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Valuation AMG Industry Range
Price/Earnings 21.1x
Price/Sales 5.4x
Price/Book 4.3x
Price/Cash Flow 20.9x
TEV/Sales 2.3x
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