Last $3.48 USD
Change Today +0.005 / 0.14%
Volume 894.5K
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As of 8:10 PM 10/21/14 All times are local (Market data is delayed by at least 15 minutes).

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array biopharma inc (ARRY) Details

Array BioPharma Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of small molecule drugs to treat patients with cancer in North America, Europe, and the Asia Pacific. Its proprietary clinical programs in Phase II clinical trial include ARRY-797, a p38 program for Lamin A/C-related dilated cardiomyopathy; and ARRY-502, a CRTh2 antagonist to treat Th2-driven allergic disease. The company’s proprietary programs also comprise Filanesib, a kinesin spindle protein inhibitor for multiple myeloma; and ARRY-614, a p38/Tie2 dual inhibitor for myelodysplastic syndromes. Its partnered clinical programs include various drug candidates, including Binimetinib, an MEK inhibitor for cancer; Selumetinib, an MEK inhibitor for cancer; ASLAN001/ARRY-543, an HER2/EGFR inhibitor for gastric cancer; Ipatasertib/GDC-0068, an AKT inhibitor for cancer; VTX-2337, a toll-like receptor for cancer; and Danoprevir, a Hepatitis C virus protease inhibitor. The company’s partnered clinical programs also comprise LY2606368, an Chk-1 inhibitor for cancer; GDC-0575, an Chk-1 inhibitor for cancer; ARRY-380/ONT-380, an HER2 inhibitor for breast cancer,; GDC-0994, an ERK inhibitor for cancer; and LOXO-101, an PanTrk inhibitor for cancer. It has collaborations with Celgene Corporation; Celgene Alpine Investment Co., LLC; Genentech, Inc.; Loxo Oncology, Inc; Novartis International Pharmaceutical Ltd.; and Oncothyreon Inc. The company was founded in 1998 and is headquartered in Boulder, Colorado.

198 Employees
Last Reported Date: 08/15/14
Founded in 1998

array biopharma inc (ARRY) Top Compensated Officers

Chief Executive Officer and Director
Total Annual Compensation: $548.8K
Co-Founder, Chief Operating Officer and Vice ...
Total Annual Compensation: $388.6K
Chief Financial Officer and Principal Account...
Total Annual Compensation: $358.1K
Vice President, General Counsel and Secretary
Total Annual Compensation: $357.5K
Senior Vice President of Commercial Operation...
Total Annual Compensation: $343.8K
Compensation as of Fiscal Year 2014.

array biopharma inc (ARRY) Key Developments

Array BioPharma Inc. Announces Phase 2 Trial of Binimetinib in NRAS Melanoma Shows

Final results from a Phase 2 trial of binimetinib in patients with advanced NRAS mutant melanoma were presented at the European Society for Medical Oncology (ESMO) Annual Meeting in Madrid, Spain. Invented by Array BioPharma Inc., binimetinib is a small molecule selective inhibitor of the kinases MEK1 and MEK2. Results from the 117 patient Phase 2 study showed median progression free survival (mPFS) of 3.6 months and objective response rate (ORR) of 14.5%, including one patient who achieved a complete response. These findings were consistent with previously disclosed interim results at the American Society of Clinical Oncology 2012 annual meeting. In addition, the median overall survival (mOS) of 12.2 months is encouraging for this patient population, which has a particularly poor prognosis. NEMO, a global phase 3 trial currently enrolling patients with NRAS mutant melanoma, is designed to measure the difference in PFS between patients treated with binimetinib versus those treated with dacarbazine, a current standard of care. Adverse events in the Phase 2 study were generally mild to moderate. The most frequently observed adverse events included acneiform dermatitis, increased blood creatine phosphokinase and peripheral edema, which are consistent with previous results reported for the MEK inhibitor class.

Array BioPharma Inc. Appoints Victor Sandor as Chief Medical Officer

Array BioPharma Inc. announced the appointment of Victor Sandor, M.D., as Chief Medical Officer. Dr. Sandor will be responsible for leading clinical, medical and regulatory strategy and operations across the Array portfolio, including binimetinib, a MEK inhibitor in Phase 3 trials for ovarian cancer and melanoma, and filanesib, a KSP inhibitor for multiple myeloma. Dr. Sandor brings a wealth of experience in oncology/hematology drug development, following a successful track record in leadership positions at premier biopharmaceutical and pharmaceutical companies, including Incyte, Biogen, and AstraZeneca. Prior to joining Array, he was Senior Vice President for Global Clinical Development at Incyte Corporation.

Array BioPharma, Inc. Presents at 2014 Morgan Stanley Global Healthcare Conference, Sep-10-2014 12:55 PM

Array BioPharma, Inc. Presents at 2014 Morgan Stanley Global Healthcare Conference, Sep-10-2014 12:55 PM. Venue: The Grand Hyatt Hotel, New York, New York, United States. Speakers: Ron Squarer, Chief Executive Officer and Director.


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