Last $8.18 USD
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As of 5:20 PM 12/26/14 All times are local (Market data is delayed by at least 15 minutes).

amicus therapeutics inc (FOLD) Snapshot

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amicus therapeutics inc (FOLD) Details

Amicus Therapeutics, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines for various rare and orphan diseases. It develops enzyme replacement therapies (ERTs) for lysosomal storage disorders (LSDs), including Fabry disease, Pompe disease, and Mucopolysaccharoidosis Type I (MPS I). The company also develops novel small molecules as monotherapy treatments for Fabry disease and Parkinson's disease. Its chaperone-advanced replacement therapy program is used to develop next-generation ERTs by co-formulating therapeutic enzymes with proprietary pharmacological chaperones. The company’s lead programs include the small molecule pharmacological chaperones, migalastat HCl as a monotherapy that is in Phase III global registration studies for Fabry patients with genetic mutations; and AT2220 (duvoglustat HCl), which has completed Phase II safety used for the treatment of Pompe disease. Its products also comprise AT-B200, a proprietary recombinant human acid-alpha glucosidase that is in late preclinical development for Pompe disease; and AT3375 for treating Gaucher disease. The company has strategic collaboration with GlaxoSmithKline PLC to develop and commercialize migalastat HCl. Amicus Therapeutics, Inc. was founded in 2002 and is based in Cranbury, New Jersey.

92 Employees
Last Reported Date: 03/3/14
Founded in 2002

amicus therapeutics inc (FOLD) Top Compensated Officers

Chairman and Chief Executive officer
Total Annual Compensation: $824.1K
Chief Financial Officer and Secretary
Total Annual Compensation: $445.1K
Chief Operating Officer
Total Annual Compensation: $475.0K
Principal Accounting Officer, Vice President ...
Total Annual Compensation: $247.4K
Compensation as of Fiscal Year 2013.

amicus therapeutics inc (FOLD) Key Developments

Amicus Therapeutics, Inc.(NasdaqGM:FOLD) added to NASDAQ Biotechnology Index

Amicus Therapeutics, Inc. will be added to the NASDAQ Biotechnology Index.

Amicus Therapeutics, Inc. Presents at Oppenheimer 25th Annual Healthcare Conference, Dec-11-2014 01:35 PM

Amicus Therapeutics, Inc. Presents at Oppenheimer 25th Annual Healthcare Conference, Dec-11-2014 01:35 PM. Venue: The Crowne Plaza Hotel, New York, New York, United States. Speakers: Chip Baird, Chief Financial Officer.

Amicus Therapeutics Announces Unaudited Consolidated Earnings Results for the Third Quarter and Nine Months Ended September 30, 2014; Provides Net Cash Spend Guidance for the Full Year 2014; Provides Program Updates

Amicus Therapeutics announced unaudited consolidated earnings results for the third quarter and nine months ended September 30, 2014. For the third quarter, the company reported total revenue of $293,000 against $39,000 a year ago. Loss from operations was $16,816,000 against $15,135,000 a year ago. Net loss was $17,149,000 or $0.22 per basic and diluted share against $14,589,000 or $0.29 per basic and diluted share a year ago. For the nine months, the company reported total revenue of $1,224,000 against $39,000 a year ago. Loss from operations was $46,703,000 against $48,391,000 a year ago. Net loss was $47,706,000 or $0.68 per basic and diluted share against $47,396,000 or $0.96 per basic and diluted share a year ago. The company provided net cash spend guidance for the full year 2014. For the year, the company continues to expect full-year 2014 net cash spend of between $54 million and $59 million. The company announced that it is developing its wholly owned pharmacological chaperone migalastat HCl (migalastat) monotherapy for the treatment of people with Fabry disease. As a monotherapy, migalastat is designed to bind and stabilize alpha-Gal A enzyme in patients with amenable mutations. Migalastat monotherapy is being investigated in two phase 3 registration studies (Study 011 and Study 012) and an open-label extension study (Study 041) in Fabry patients with amenable mutations. Positive phase 3 results from study 011 reported at american society of human genetics (ASHG) annual meeting: In October 2014, positive results from Study 011 and Study 041 were presented in a poster at ASHG by Daniel G. Bichet, M.D., M.Sc., Professor, Department of Physiology, University of Montreal. Data presented showed that patients receiving migalastat for an average of 32 months showed continued stability of kidney function and compared favorably to published natural history in Fabry disease. Decline in kidney function is a key cause of morbidity and mortality in patients with Fabry disease. Data from Study 012 will be presented at a scientific congress for the first time at the American Society of Nephrology (ASN) Kidney Week 2014 in Philadelphia on November 15, 2014. The data will be in a poster entitled Migalastat and Enzyme Replacement Therapy Have Comparable Effects on Renal Function in Fabry Disease: Phase 3 study results. This presentation will also include important new data on cardiac and other key secondary endpoints from Study 012. Based on the positive results from Study 012, Amicus expects to submit a marketing application for migalastat monotherapy in Europe, and is scheduled to meet with the European Medicines Agency in the fourth quarter of this year. Amicus also plans to meet with the U.S. Food and Drug Administration in the first quarter of 2015 to discuss the data from both Phase 3 Fabry monotherapy studies to determine the fast U.S. registration pathway for migalastat.


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