Last $4.93 USD
Change Today -0.02 / -0.40%
Volume 63.2K
ONTX On Other Exchanges
As of 5:20 PM 07/30/14 All times are local (Market data is delayed by at least 15 minutes).

onconova therapeutics inc (ONTX) Snapshot

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52 Week High
10/4/13 - $31.13
52 Week Low
06/5/14 - $4.10
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Average Volume 10 Days
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onconova therapeutics inc (ONTX) Details

Onconova Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule drug candidates to treat cancer. Its clinical-stage product candidates include rigosertib intravenous that is in Phase III trials for higher risk myelodysplastic syndromes (MDS); rigosertib Oral, which is Phase II clinical trials for patients with transfusion-dependent lower risk MDS and in patients with head and neck cancers; and a combination of rigosertib Oral and azacitidine in a Phase 1/2 study of first-line MDS patients. The company’s clinical-stage product candidates also comprise ON 013105, a small molecule targeting an important regulatory protein, cyclin D1, which is found at elevated levels in cancer cells; and recilisib, a molecule with radiation protection properties has completed four Phase I clinical trials. In addition, its preclinical products consist of ON 1231320, an inhibitor of polo-like kinase 2; ON 123300, an inhibitor of the cell cycle and cancer cell metabolism; ON 108600, an inhibitor of cyclin-dependent kinase 9 and casein kinase 2; ON 044580, a dual inhibitor of janus kinase 2 and Bcr-Abl kinase; ON 24 series of compounds that are oral anti-tubulin agents; and ON 146 series, which are selective inhibitors of PI3K alpha/delta isoforms. It has a development and license agreement with Baxter Healthcare SA; and a license agreement with SymBio Pharmaceuticals Limited. The company was founded in 1998 and is headquartered in Newtown, Pennsylvania.

64 Employees
Last Reported Date: 03/20/14
Founded in 1998

onconova therapeutics inc (ONTX) Top Compensated Officers

Co-Founder, Chief Executive Officer, Presiden...
Total Annual Compensation: $742.8K
Chief Financial Officer and Secretary
Total Annual Compensation: $347.9K
President of Research and Development
Total Annual Compensation: $359.0K
Chief Medical Officer and Senior Vice Preside...
Total Annual Compensation: $487.0K
Senior Vice President of Product Development
Total Annual Compensation: $424.8K
Compensation as of Fiscal Year 2013.

onconova therapeutics inc (ONTX) Key Developments

Onconova Therapeutics, Inc.(NasdaqGS:ONTX) dropped from Russell 2000 Index

Onconova Therapeutics, Inc. will be removed from the Russell 2000 Index.

Onconova Therapeutics, Inc.(NasdaqGS:ONTX) dropped from Russell 3000 Index

Onconova Therapeutics, Inc. will be removed from the Russell 3000 Index.

Onconova Therapeutics, Inc. Presents at BIO International Convention, Jun-24-2014 11:00 AM

Onconova Therapeutics, Inc. Presents at BIO International Convention, Jun-24-2014 11:00 AM. Venue: San Diego Convention Center, San Diego, California, United States.


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Price/Sales 26.1x
Price/Book 1.7x
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TEV/Sales 5.4x

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