Last €22.18 EUR
Change Today -0.17 / -0.76%
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As of 6:12 AM 04/23/14 All times are local (Market data is delayed by at least 15 minutes).

pfizer inc-idr (PFEBC) Snapshot

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11/25/13 - €23.79
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pfizer inc-idr (PFEBC) Details

Pfizer Inc., a biopharmaceutical company, discovers, develops, manufactures, and sells healthcare products worldwide. Its product portfolio includes medicines and vaccines, as well as various consumer healthcare products. The company’s Primary Care segment offers prescription pharmaceutical products primarily prescribed by primary-care physicians for various therapeutic and disease areas comprising Alzheimer’s disease, cardiovascular, erectile dysfunction, genitourinary, major depressive disorder, pain, respiratory, and smoking cessation. Its Specialty Care and Oncology segment provides prescription pharmaceutical products for anti-infectives, endocrine disorders, hemophilia, inflammation, ophthalmology, pulmonary arterial hypertension, specialty neuroscience, and vaccines, as well as oncology and oncology-related illnesses. The company’s Established Products and Emerging Markets segment offers prescription pharmaceutical products that had lost patent protection or marketing exclusivity in certain countries and/or regions, as well as sold in emerging markets, including Asia, Latin America, the Middle East, Eastern Europe, Africa, Turkey, and Central Europe. Its Consumer Healthcare segment provides non-prescription products in a range of therapeutic categories, such as dietary supplements, pain management, respiratory, and personal care. The company primarily offers biopharmaceutical products, including Lyrica, the Prevnar family of products, Enbrel, Celebrex, Lipitor, Viagra, Zyvox, Norvasc, Sutent, and the Premarin family of products; and consumer healthcare products under the Advil, Caltrate, Centrum, ChapStick, Emergen-C, Preparation H, and Robitussin brands. It sells its products to wholesalers, distributors, retailers, hospitals, clinics, government agencies, pharmacies, individual provider offices, and grocery and convenience stores. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.

77,700 Employees
Last Reported Date: 02/28/14
Founded in 1849

pfizer inc-idr (PFEBC) Top Compensated Officers

Chairman, Chief Executive Officer and Chairma...
Total Annual Compensation: $1.8M
Chief Financial Officer and Executive Vice Pr...
Total Annual Compensation: $1.2M
President of Worldwide Research and Developme...
Total Annual Compensation: $1.1M
Group President of Global Innovative Pharma B...
Total Annual Compensation: $926.3K
Group President of Global Established Pharma ...
Total Annual Compensation: $810.1K
Compensation as of Fiscal Year 2013.

pfizer inc-idr (PFEBC) Key Developments

Pfizer Reportedly Plans AstraZeneca’s Acquisition

Pfizer Inc. (NYSE:PFE) has made a tentative approach to AstraZeneca PLC (LSE:AZN) about a possible takeover that could value the company at more than £60 billion. Informal conversations about a possible tie-up have taken place in recent weeks, according to senior investment bankers and industry sources. According to Reuters, Pfizer and AstraZeneca both declined to comment.

Pfizer and Acura Pharmaceuticals Terminate License Agreement for AVERSION and OXECTA

Pfizer and Acura Pharmaceuticals, Inc. announced that they will be terminating their license, development and commercialization agreement covering ACUR's proprietary drug abuse deterrent and tamper-resistant technologies, AVERSION and OXECTA. The license grant for ACUR's AVERSION technology will terminate effective April 9, 2014 and PFE will no longer have a right to develop, market or sell any products using this technology. ACUR will own all rights to OXECTA (oxycodone hydrochloride) Tablets CII, except for the OXECTA trademark, which will be retained by PFE. PFE received U.S. Food and Drug Administration (FDA) approval for its New Drug Application (NDA) for OXECTA in June 2011. PFE will also transfer to ACUR all studies, data, regulatory filings (including the NDA) and other information relating to OXECTA Tablets CII pursuant to a transition process. ACUR will pay PFE a one-time payment of $2 million in consideration of the termination of the license agreement.

Pfizer Inc. Announces Detailed Results from the PALOMA-1 Study

Pfizer Inc. announced detailed results from the PALOMA-1 study, a randomized Phase 2 study of palbociclib (PD-0332991) in combination with letrozole. PALOMA-1 achieved its primary endpoint by significantly prolonging progression-free survival (PFS) compared with letrozole alone in post-menopausal women with estrogen receptor positive (ER+), human epidermal growth factor receptor 2 negative (HER2-) locally advanced or metastatic breast cancer. For women treated with the combination of palbociclib plus letrozole, the median PFS was 20.2 months, a statistically significant improvement compared to the 10.2 months of PFS in women who received letrozole alone (HR=0.488 [95% CI: 0.319, 0.748]; p=0.0004). These data will be presented by Dr. Richard S. Finn, associate professor of medicine at University of California, Los Angeles (UCLA) at the American Association of Cancer Research Annual Meeting 2014 in San Diego (Abstract #CT101). Final results for the secondary efficacy endpoints of duration of treatment and clinical benefit rate demonstrated superiority in the palbociclib plus letrozole arm compared to the letrozole-only arm. Per the PALOMA-1 trial protocol, an initial assessment of overall survival (OS), a secondary endpoint, was also performed. Based on the events at the time of the assessment, a median OS of 37.5 months was observed in the combination arm versus 33.3 months for those who received letrozole alone, a difference of 4.2 months (HR = 0.813, 95% CI: 0.492, 1.345). This OS observation at the time of final PFS analysis was not statistically significant. A follow-up OS analysis will be conducted following the accrual of additional events. The combination of palbociclib and letrozole was generally well-tolerated and the safety profile of the combination was consistent with previously reported data. The most common adverse events in the palbociclib plus letrozole arm were neutropenia (a decrease of the neutrophil count), leukopenia (a decrease in the total white blood cell count), fatigue and anemia. The neutropenia observed with the combination in this study was non-cumulative and clinically manageable. No cases of febrile neutropenia were reported in either arm of the study. Neutropenia is an on-target, anti-proliferative side effect of palbociclib and signifies inhibition of CDK4 and its effect on bone marrow. Palbociclib received Breakthrough Therapy designation from the United States Food and Drug Administration (FDA) in April 2013, for the initial treatment of women with advanced or metastatic ER+, HER2- breast cancer. This designation was based on interim data from the PALOMA-1 trial. Pfizer continues to work with the FDA and other regulatory authorities to define the appropriate regulatory path forward for palbociclib.


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Price/Sales 3.9x
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Price/Cash Flow 7.4x
TEV/Sales 2.5x

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