Last $20.85 USD
Change Today +0.90 / 4.51%
Volume 774.7K
TTPH On Other Exchanges
As of 8:10 PM 10/1/14 All times are local (Market data is delayed by at least 15 minutes).

tetraphase pharmaceuticals i (TTPH) Snapshot

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tetraphase pharmaceuticals i (TTPH) Details

Tetraphase Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, develops various antibiotics for the treatment of serious and life-threatening multi-drug resistant infections. Its lead product candidate is eravacycline, an intravenous and oral antibiotic for use as a first-line empiric monotherapy for the treatment of multidrug-resistant infections, including multidrug-resistant Gram-negative bacteria. The company is conducting a Phase III clinical trial of eravacycline with intravenous administration for the treatment of complicated intra-abdominal infections; and a second Phase III clinical trial of eravacycline for the treatment of complicated urinary tract infections with intravenous-to-oral step-down therapy. It is also developing TP-271, a preclinical compound for respiratory diseases caused by bacterial biothreat pathogens; and preclinical Gram-negative program for multidrug-resistant Gram-negative infections. The company was founded in 2006 and is headquartered in Watertown, Massachusetts.

46 Employees
Last Reported Date: 03/6/14
Founded in 2006

tetraphase pharmaceuticals i (TTPH) Top Compensated Officers

Chief Executive Officer, President and Direct...
Total Annual Compensation: $394.2K
Chief Financial Officer, Principal Accounting...
Total Annual Compensation: $293.8K
Chief Medical Officer
Total Annual Compensation: $338.2K
Senior Vice President of Biology
Total Annual Compensation: $273.0K
Compensation as of Fiscal Year 2013.

tetraphase pharmaceuticals i (TTPH) Key Developments

Tetraphase Pharmaceuticals, Inc. Presents at The 21st Annual NewsMakers in the Biotech Industry 2014, Sep-26-2014 02:00 PM

Tetraphase Pharmaceuticals, Inc. Presents at The 21st Annual NewsMakers in the Biotech Industry 2014, Sep-26-2014 02:00 PM. Venue: Millennium Broadway Hotel & Conference Center, 145 West 44th Street, New York, New York, United States. Speakers: Guy MacDonald, Chief Executive Officer, President and Director.

Tetraphase Pharmaceuticals, Inc. - Special Call

To discuss the top-line data from the lead-in portion of the IGNITE 2 Phase 3 trial

Tetraphase Pharmaceuticals, Inc. Announces Oral Dosing Data from Lead-In of Ignite 2 Phase 3 Trial of Eravacycline in Cuti Support Advancement to Pivotal Portion

Tetraphase Pharmaceuticals, Inc. announced that positive top-line results from the lead-in portion of its IGNITE 2 clinical trial, a two-part Phase 3 clinical trial studying the efficacy and safety of intravenous (IV) and oral formulations of eravacycline for the treatment of complicated urinary tract infections (cUTI), support advancement of the trial into its pivotal portion. Data from the lead-in portion demonstrated that both IV-to-oral dosing regimens of eravacycline (1.5 mg/kg IV followed by 200 mg or 250 mg) compared favorably to levofloxicin. The responder outcome (the primary endpoint for the FDA) for the IV-to-oral 200 mg, IV-to-oral 250 mg and levofloxacin groups were 70.8%, 64.3% and 52.2%, respectively. The microbiological response (the primary endpoint for the European Medicines Agency) were 75.0%, 64.3% and 56.5%, respectively. The pharmacokinetics of both oral doses of eravacycline were comparable to the IV formulation. Overall, treatment was generally well tolerated in all three groups with the most common adverse events reported being nausea and emesis. Only two patients discontinued treatment as a result of drug related adverse events.


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Price/Sales 66.1x
Price/Book 8.9x
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TEV/Sales 55.8x

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