Last 0.38 GBp
Change Today 0.00 / 0.00%
Volume 1.8M
VAL On Other Exchanges
As of 5:35 AM 07/24/14 All times are local (Market data is delayed by at least 15 minutes).

valirx plc (VAL) Snapshot

0.38 GBp
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52 Week High
10/25/13 - 0.71 GBp
52 Week Low
04/28/14 - 0.26 GBp
Market Cap
Average Volume 10 Days
-0.0019 GBp
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Dividend Yield
Current Stock Chart for VALIRX PLC (VAL)

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valirx plc (VAL) Details

ValiRx Plc, an investment holding company, is engaged in the research and development of technologies and products in oncology therapeutics and diagnostics in the United Kingdom. The company operates in two segments, Drug Development and Sale of Self-Test Drug Kits. Its proprietary GeneICE technology enables selective silencing of rebellious genes, which cause cancers, inflammatory conditions, and Alzheimer’s and autoimmune diseases. The company’s lead drug candidates in late stage pre-clinical development include VAL101, a novel therapeutic based on GeneICE platform that acts to target and switch off the Bcl-2 gene, a protein that inhibits the process of apoptosis; and VAL201, a novel peptide for the treatment of hormone refractory prostate cancer, and other indications of hormone induced unregulated growth, including endometriosis. It is also developing ValiFinn BioMarkers that are diagnostic markers of inhibition of signaling pathways, which are target sites for novel drugs to treat cancer; and predictive markers of disease progression, as well as VAL401, a clinical drug to treat patients with lung cancer. The company is based in London, the United Kingdom.

9 Employees
Last Reported Date: 03/28/14

valirx plc (VAL) Top Compensated Officers

Chief Executive Officer, Director and Member ...
Total Annual Compensation: 182.5K GBP
Chief Financial Officer, Director and Member ...
Total Annual Compensation: 74.0K GBP
Chief Operating Officer and Director
Total Annual Compensation: 118.0K GBP
Compensation as of Fiscal Year 2013.

valirx plc (VAL) Key Developments

ValiRx plc Announces Joint Venture with Tangent Reprofiling Ltd

ValiRx Plc announced that it had set up a majority-owned joint venture with Tangent Reprofiling Ltd. to advance the development of a lung cancer drug.

ValiRx plc Announces New Office Address

ValiRx Plc announced that it has moved offices to better accommodate its growing team. The company's new office address is: 3rd Floor, 16 Upper Woburn Place, London, WC1H 0BS.

ValiRx plc Provides Development Update

ValiRx Plc provided a positive development and scientific update on the first month's progress at ValiSeek Limited, ValiRx's joint venture company with Tangent Reprofiling Limited. ValiSeek was formed to progress the novel cancer treatment VAL401 through its remaining preclinical development and towards clinical Phase II trials for the treatment of lung cancer and other oncology indications. The company reported that key results from non-regulatory toxicology studies confirmed that the VAL401 formulation is well tolerated in dosing schedule. These results therefore allow ValiSeek to plan future detailed regulatory toxicology and pharmacokinetic studies with greater confidence in securing a positive outcome for clinical studies. Furthermore, the combination of components in the reformulation showed comparable results to prior data from the previous clinical usage of the drug permitting ValiSeek to better understand the regulatory route through to the clinic. Further in vitro results have encouraged ValiSeek to investigate the precise subsets of patients suitable for clinical treatment with VAL401. Specifically, non-small cell lung cancer (adenocarcinoma, non-squamous) and small cell lung adenocarcinoma cell lines responded well to VAL401 treatment in vitro, expanding previous results. ValiSeek is now able to identify which cell lines to take forward into the next stage of studies and to make better informed clinical decisions on the selection of trial patients. Further to the lung cancer indication, new results have indicated potential utility in pancreatic cancer, with the cellular in vitro assay with pancreatic cancer cells responding in a comparable degree to the lung cancer cells. This complements earlier studies by Tangent, which also suggest utility in both prostate cancer and breast cancer, demonstrating the potential for broad spectrum use of VAL401 against solid adenocarcinoma tumours or cancers of hormone responsive glandular origin.


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