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Company Description

Contact Info

980 Great West Road

Brentford, TW8 9GS

United Kingdom

Phone: 44 20 8047 5000

Fax: 44 20 8047 7807

www.gsk.com

GlaxoSmithKline plc operates as a healthcare company worldwide. The company engages in the creation and discovery, development, manufacture, and marketing of pharmaceutical products, including vaccines, over-the-counter medicines, and health-related consumer products. The company’s principal pharmaceutical products include medicines in various therapeutic areas, such as respiratory, anti-virals, central nervous system, cardiovascular and urogenital, metabolic, antibacterials, oncology and emesis, dermatology, rare diseases, immuno-inflammation, vaccines, and HIV. It manufactures and distributes approximately 4 billion packs of products to approximately 150 countries worldwide. Businesses The company has three primary areas of business, such as Pharmaceuticals, Vaccines, and Consumer Healthcare. Pharmaceuticals The company’s Pharmaceuticals business develops and makes available medicines to treat a range of serious and chronic diseases. Its portfolio is made up of established brands and patent-protected medicines. Products Respiratory: The company’s products include Veramyst for the treatment of rhinitis; and Flixotide/Flovent, Seretide/Advair, Serevent, and Ventolin HFA for the treatment of asthma/COPD. Anti-Virals: The company’s products include Relenza for the treatment of influenza; Valtrex for the treatment of genital herpes, coldsores, and shingles; and Zeffix/Epivir-HBV for the treatment of chronic hepatitis B. Central Nervous System: The company’s products include Lamictal for the treatment of epilepsy and bipolar disorder; Imigran/Imitrex for the treatment of migraine; Requip XL for the treatment of Parkinson’s disease; Seroxat/Paxil for the treatment of depression and various anxiety disorders; Treximet for the treatment of migraine; and Wellbutrin for the treatment of depression. Cardiovascular and Urogenital: The company’s products include Arixtra used for the treatment of deep vein thrombosis and pulmonary embolism; Avodart for the treatment of benign prostatic hyperplasia; Benlysta for the treatment of systemic lupus erychematosus; Coreg CR for the treatment of mild-to-severe heart failure, hypertension, and left ventricular dysfunction post MI; Fraxiparine for the treatment of deep vein thrombosis and pulmonary embolism; Lovaza for the treatment of triglycerides; and Volibris for the treatment of pulmonary hypertension. Anti-Bacterials: The company’s product includes Augmentin for the treatment of common bacterial potassium infections. Oncology: The company’s products include Arzerra for the treatment of refractory chronic lymphocytic leukaemia; Hycamtin for the treatment of ovarian cancer, small cell lung cancer, and cervical cancer; Promacta/Revolade for the treatment of idiopathic thrombocytopenic purpura; Tykerb/Tyverb for the treatment of advanced and metastatic breast cancer in HER2 positive patients; and Votrient for the treatment of soft tissue sarcoma metastatic renal cell carcinoma. HIV: The company’s products include Combivir, Epivir, Epzicom/Kivexa, Lexiva, Selzentry, and Trizivir for the treatment of HIV/AIDS. Vaccines The company’s Vaccines business produces paediatric and adult vaccines against a range of infectious diseases. In 2012, it distributed approximately 900 million doses to 170 countries. The company’s products include Boostrix for the treatment of booster vaccination; Infanrix/Pediarix for diphtheria, tetanus, pertussis, polio, and hepatitis B; Cervarix for the treatment of human papilloma virus type 16 and 18; Fluarix and FluLaval for seasonal influenza; Pandemrix for A(H1N1)v2009 influenza prophylaxis; Prepandrix for influenza prophylaxis; and Synflorix for invasive pneumococcal disease. Consumer Healthcare The company’s Consumer Healthcare business develops and markets a range of consumer health products based on scientific innovation. It has brands in four primary categories, such as Total wellness, Oral care, Nutrition, and Skin health. Total Wellness: The company’s products include Panadol for the treatment of paracetamol-based treatment of headache and joint pain, fever, and cold symptoms; NicoDerm, NiQuitin CQ, and Nic

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